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ProteomicsK. pneumoniae phosphoproteome - Systematic profiling of the bacterial phosphoproteome reveals bacterium-specific features of phosphorylation
Highly efficient phosphopeptide enrichment developed for bacterial phosphoproteomics. The most comprehensive phosphoproteme maps in both gram-positive/negative bacteria. Discovery of phosphorylation motifs across distinct bacterial species
ORGANISM(S): Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 
2015-09-22 | PXD001263 | Pride
Phosphorylation K. pneumoniae Lc-msms 
UnknownThe Na<sup>+</sup>,K<sup>+</sup>,2Cl<sup>-</sup> Cotransporter, Not Aquaporin 1, Sustains Cerebrospinal Fluid Secretion While Controlling Brain K<sup>+</sup> Homeostasis.
Not available
S-EPMC11809428 | biostudies-literature
MetabolomicsDiel metabolomics analysis of a hot spring chlorophototrophic microbial mat leads to new hypotheses of community member metabolisms
Dynamic environmental factors such as light, nutrients, salt, and temperature continuously affect chlorophototrophic microbial mats, requiring adaptive and acclimative responses to stabilize composition and function. Quantitative metabolomics analysis can provide insights into metabolite dynamics fo...
2024-02-23 | MTBLS187 | MetaboLights
ProteomicsIdentification of SUMO targets required to maintain human stem cells in the pluripotent state. - Identification of SUMO modified proteins from hiPS cells
To determine the role of SUMO modification in the maintenance of pluripotent stem cells we used ML792, a potent and selective inhibitor of SUMO Activating Enzyme. Treatment of human induced pluripotent stem cells with ML792 initiated changes associated with loss of pluripotency such as reduced expre...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD028050 | Pride
Sumo Hipsc Stem cells 
UnknownKir 5.1-dependent CO2 /H+ -sensitive currents contribute to astrocyte heterogeneity across brain regions.
Not available
S-EPMC8665280 | biostudies-literature
UnknownInhibition of KCa2 and Kv11.1 Channels in Pigs With Left Ventricular Dysfunction.
Not available
S-EPMC7219273 | biostudies-literature
ProteomicsMps1 regulates kinetochore-microtubule attachment stability via the Ska complex to ensure error-free chromosome segregation
Spindle assembly checkpoint (SAC) regulators such as the Mps1 kinase not only delay anaphase onset, but also correct improper chromosome-spindle linkages that would otherwise lead to missegregation and aneuploidy. However, the substrates and mechanisms involved in this pathway of error correction re...
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD006135 | Pride
Proteomics Mps1 Chemical genetics Ska complex Spindle assembly checkpoint (sac) Pp2a-b56 
ProteomicsExtending the coverage of Lys-C/trypsin-based bottom-up proteomics using cysteine S-aminoethylation
In this study, S-aminoethylation of Cys (AE-Cys) was carried out with 2-bromoethylamine to form pseudo-Lys, which was then digested with Lys-C or trypsin to improve proteome coverage in bottom-up proteomics. A model study with bovine serum albumin showed that the C-terminal side of Cys was successfu...
ORGANISM(S): Homo Sapiens (human) Bos Taurus 
2023-09-27 | PXD045433 | JPOST Repository
TranscriptomicsGlobal gene expression analysis of Salmonella enterica serovar Enteritidis during growth in whole egg
Even though the incidence of salmonellosis in humans has decreased over the last years, Salmonella spp. are still a leading cause of foodborne outbreaks in Europe (Anon., 2014). Of more than 2500 different serovars of Salmonella enterica, S. enterica serovar Enteritidis (S. Enteritidis) is the most ...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Enteritidis 
2016-03-04 | E-MTAB-4521 | biostudies-arrayexpress
ProteomicsComparative proteome analysis across non-small cell lung cancer cell lines
Non-small cell lung cancer (NSCLC) cell lines are widely used model systems to study molecular aspects of lung cancer. Comparative and in-depth proteome expression data across many NSCLC cell lines has not been generated yet, but would be of utility for the investigation of candidate targets and mar...
ORGANISM(S): Homo sapiens (Human) 
2015-09-14 | PXD002556 | Pride
Pca Non-small cell lung cancer K-ras Silac Proteome profiling Egfr 
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