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ProteomicsA PrSM-level Side-by-Side Comparison of On-line LCMS methods on Intact Histone H3 and H4 Proteoforms
The heterogeneity of histone H3 proteoforms has made histone H3 top-down analysis challenging. To enhance the detection coverage on the proteoforms, performing liquid chromatography (LC) front-end to MS detection is recommended. Here, by using optimized Electron-Transfer/High-Energy Collision Dissoc...
ORGANISM(S): Homo sapiens (Human) 
2025-03-03 | PXD026820 | Pride
Top-down proteomics Histones Post-translation modifications On-line lcms Rplc Esi-compatible wcx/hilic 
ProteomicsProtein identification of cytotoxins isolated from Malaysian Naja sumatrana and Thai Naja kaouthia
Identification of cytotoxins using nano-ESI-LCMS/MS
ORGANISM(S): Naja Sumatrana Naja Kaouthia 
2020-09-08 | PXD021350 |
MetabolomicsWolbachia modulation of lipid metabolism in Aedes albopictus mosquito cells
Certain strains of the intracellular endosymbiont Wolbachia can strongly inhibit or block the transmission of viruses such as dengue by Aedes mosquitoes, and the mechanisms responsible are still not well understood. Direct infusion and liquid chromatography FT-ICR mass spectrometry based lipidomicse...
MTBLS210 | MetaboLights
ProteomicsProteome changes in a human retinal pigment epithelial cell line during oxidative stress and following antioxidant treatment
Evaluation of the quantitative changes in Proteome caused by oxidative stress in the presence/absence of vitamin E compounds
ORGANISM(S): Homo sapiens (Human) 
2023-04-17 | PXD039513 | Pride
Human Oxidative stress Retina 
ProteomicsKM-12 Whole Cell Lysate Proteomics
The KM-12 cell line, representative of colorectal cancer indications, was used to explore the effect that multiple compounds would have in the profile of transcription factor occupancy. Cells were dosed with 3 concentrations of each of the 5 compounds provided for 3 different timepoints. Both a chro...
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD065035 | Pride
Lc-msms Colorectal cancer Timstof 
MetabolomicsMolecular Basis Underlying Common Cutworm Resistance of the Primitive Soybean Landrace Peking

The common cutworm (CCW; Spodoptera litura) is one of the major insect pests of soybean in Asia and Oceania. Although quantitative trail loci related to CCW resistance have been introduced into leading soybean cultivars, these do not exhibit sufficient resistance against CCW. Thus, under...

2020-11-06 | MTBLS1960 | MetaboLights
UnknownDrug level testing as a strategy to determine eligibility for drug resistance testing after failure of ART: a retrospective analysis of South African adult patients on second-line ART.
Not available
S-EPMC7282495 | biostudies-literature
MetabolomicsDietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism

Ferroptosis is mediated by lipid peroxidation of phospholipids containing polyunsaturated fatty acyl moieties. Glutathione, the key cellular antioxidant capable of inhibiting lipid peroxidation via the activity of the enzyme glutathione peroxidase 4 (GPX-4), is generated directly from the sulfur-...

2023-01-11 | MTBLS5959 | MetaboLights
MetabolomicsMetabolic analysis of two wheat (Triticum aestivum) cultivars in response to Russian wheat aphid (Diuraphis noxia Kurdjumov) infestation
Wheat is one of the most widely consumed cereal grains globally and plays a critical role in food security. As a staple crop in many households, it provides essential nutrients and contributes significantly to daily caloric intake. Although wheat is attacked by multiple pests, the Russian wheat aphi...
2026-06-23 | MTBLS14820 | MetaboLights
ProteomicsImmunopeptidome analysis of 4T1 murine breast cancer cells.
This study aimed to identify Tumor Associated Antigens (TAA)s by Immunoaffinity purification of MHC peptides and LCMS analysis, verifying their immunogenicity and testing their tumor control potential in a highly aggressive preclinical model of triple-negative breast cancer in mice. Among the MHC pe...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-10 | PXD016112 | Pride
Cancer Ligandome Orbitrap fusion Mouse Murine Immunopeptidome Mhc-i 4t1 
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