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TranscriptomicsIntracellular expression pattern of recombinant Mtb strain TB294 overexpressing sigma factor A
We previously showed that increased expression of the principal sigma factor, SigA, mediates the capacity of Mycobacterium tuberculosis 210 strains to grow more rapidly in human monocytes, compared to other strains. To identify SigA-regulated genes that favor intracellular mycobacterial growth, we u...
ORGANISM(S): Mycobacterium tuberculosis 
2010-10-08 | E-GEOD-13780 | biostudies-arrayexpress
UnknownCharacterization of Thermostable Cellulase from Bacillus licheniformis PANG L Isolated from the Himalayan Soil.
Not available
S-EPMC10484656 | biostudies-literature
TranscriptomicsCoordination of frontline defense mechanisms under severe oxidative stress.
Oxidative stress (OS) results from genetic defects or stressful environmental challenges that cause unchecked production of reactive oxygen species (ROS). OS has been implicated in many diseases due to its wide ranging damage to nucleic acids, proteins and lipids. Using Halobacterium salinarum NRC...
ORGANISM(S): Halobacterium salinarum 
2010-05-26 | E-GEOD-17515 | biostudies-arrayexpress
ProteomicsGenome- and proteome-wide analysis of lysine acetylation in Vibrio vulnificus Vv180806 reveals its regulatory roles in virulence and antibiotic resistance
V. vulnificus is an emergent pathogen and causes deadly septicemia in human. Protein acetylation regulates many important biological processes in bacteria. In this study, we identified the first lysine acetylome of V. vulnificus based on the whole-genome sequence of a cefoxitin-resistant strain isol...
ORGANISM(S): Vibrio vulnificus VV 
2020-12-01 | PXD020376 | Pride
Vibrio vulnificus  whole genome sequencing  acetylome  virulence  antibiotic resistance 
TranscriptomicsComparison of gene expression profile of human trabecular meshwork cells induced by triamcinolone with dexamethasone
PURPOSE. Triamcinolone acetonide (TA) and dexamethasone (DEX) are corticosteroids commonly used for ocular inflammation but both can cause ocular hypertension. We investigated the differential gene expression profile of human trabecular meshwork (TM) cells in response to treatment by TA compared to ...
ORGANISM(S): Homo sapiens 
2008-05-01 | E-GEOD-6298 | biostudies-arrayexpress
ProteomicsCampylobacter concisus strain BAA-1547 GeLC-MSMS
Bacteria were washed three times in NaCl (150 mM). Cells were resuspended in 1 ml TSU buffer (50 mM Tris pH 8.0, 0.1% SDS, 2.5 M urea) and lysed by two freeze-thaw cycles in liquid nitrogen. Lysate proteins (40 ug) were separated and digested. Digested peptides were separated by nano-LC using an U...
ORGANISM(S): Campylobacter concisus (strain 13826) 
2014-04-28 | PXD000504 | Pride
Concisus Gelc-msms Campylobacter 
ProteomicsCampylobacter concisus UNSWCD GeLC-MSMS
Washed three times in NaCl (150 mM). Cells were resuspended in 1 ml TSU buffer (50 mM Tris pH 8.0, 0.1% SDS, 2.5 M urea) and lysed by two freeze-thaw cycles in liquid nitrogen. Lysate proteins (40 ug) were separated and digested. Digested peptides were separated by nano-LC using an Ultimate 3000 ...
ORGANISM(S): Campylobacter concisus UNSWCD 
2014-04-28 | PXD000505 | Pride
Concisus Gelc-msms Campylobacter 
MetabolomicsBranched-chain ketoacids derived from cancer cells modulate macrophage polarization and metabolic reprogramming

Macrophages are prominent immune cells in the tumor microenvironment that can be educated into pro-tumoral phenotype by tumor cells to favor tumor growth and metastasis. The mechanisms that mediate a mutualistic relationship between tumor cells and macrophages remain poorly characterized. Here, w...

2022-10-03 | MTBLS4497 | MetaboLights
MetabolomicsUntargeted metabolomics analysis of intestinal contents in Common Carp

To elucidate the metabolic mechanisms underlying the beneficial effects of Enterococcus faecalis on host health under high-carbohydrate-high-fat (HCHF) stress, we performed an untargeted metabolomics analysis on intestinal contents of common carp (Cyprinus carpio). Fish were fed an HCHF diet with...

2026-08-09 | MTBLS15296 | MetaboLights
TranscriptomicsGene expression analysis of RB1 knockdown in bone in response to radiation
The role of RB1 in response to radiation was examined in human osteoblasts. We demonstrate that RB1 induced SASP genes, a response which was attenuated in RB1 knockdown osteoblasts. Subconfluent hOB shEV and shRB1 cells were irradiated at 4 Gy using a 137Cesium source at a dose rate of 1.7 min/Gy a...
ORGANISM(S): Homo sapiens 
2013-09-14 | E-GEOD-50532 | biostudies-arrayexpress
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