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TranscriptomicsTranscription profiling time series toxicogenomic profiles in CD-1 mice after nontoxic and nonlethal hepatotoxic paracetamol administration
Effect of vehicle vs non-toxic and toxic paracetamol (151mg/kg and 529mg/kg) doses on the gene expression profile at 1, 4 and 24h in murine liver.
ORGANISM(S): Mus musculus 
2004-02-20 | E-MEXP-82 | biostudies-arrayexpress
GenomicsGene expression analysis of hESCs undergoing neuronal differentiation exposed to paracetamol [RNA-seq]
Gene expression analysis of hESCs undergoing neuronal differentiation exposed to paracetamol [RNA-seq]
PRJNA908093 | ENA
TranscriptomicsGeneric drug screen identifies paracetamol as 5-aza-2’-deoxycytidine sensitizer in head and neck squamous cell carcinoma cells
Aberrant DNA methylation (5mC) is one of the key characteristics of many cancers including head and neck squamous cell carcinoma (HNSCC). The DNA demethylating agent 5-aza-2’-deoxycytidine (DAC) has anti-cancer therapeutic potential, but its clinical efficacy is currently hindered by dose-limiting s...
ORGANISM(S): Homo sapiens 
2018-11-02 | GSE110045 | GEO
GenomicsSingle-cell ATAC-seq analysis of hESCs undergoing neuronal differentiation exposed to paracetamol [scATAC-seq]
Single-cell ATAC-seq analysis of hESCs undergoing neuronal differentiation exposed to paracetamol [scATAC-seq]
PRJNA908094 | ENA
ProteomicsUncovering the mechanisms responsible for intravenous paracetamol-induced hypotension
Intravenous (IV) administration of paracetamol (APAP) is well-documented to cause severe hypotension, particularly in critically ill patients. We have previously shown that a metabolite of APAP – N-acetyl-p-benzoquinone imine (NAPQI) – is a potent vasodilator, but whether APAP can be metabolised to ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-20 | PXD047218 | Pride
Napqi Acetaminophen Endothelium Cyp20a1 Myeloperoxidase Paracetamol 
GenomicsNext Generation Sequencing timecourse of murine hepatocytes with or without paracetamol treatment
Next Generation Sequencing timecourse of murine hepatocytes with or without paracetamol treatment
PRJNA547765 | ENA
GenomicsGeneric drug screen identifies paracetamol as 5-aza-2’-deoxycytidine sensitizer in head and neck squamous cell carcinoma cells
Generic drug screen identifies paracetamol as 5-aza-2’-deoxycytidine sensitizer in head and neck squamous cell carcinoma cells
PRJNA432654 | ENA
GenomicsSingle-cell gene expression analysis of hESCs undergoing neuronal differentiation upon exposure to paracetamol [scRNA-seq]
Single-cell gene expression analysis of hESCs undergoing neuronal differentiation upon exposure to paracetamol [scRNA-seq]
PRJNA908092 | ENA
UnknownParacetamol versus Paracetamol Plus Ondansetron on Acute Postoperative Pain.
Not available
S-EPMC8674094 | biostudies-literature
GenomicsSingle-cell ATAC-seq analysis of hESCs undergoing neuronal differentiation exposed to paracetamol [scATAC-seq]
Genome-wide chromatin opening profiling of hESCs undergoing neuronal differentiation at four distinct time-points. hESCs are differentiated using a neuronal protocol, and day 20 were charachterized. Cells exposed to 100 or 200 μM paracetamol from Day 1.
ORGANISM(S): Homo sapiens 
2023-08-31 | GSE220026 | GEO
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