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ProteomicsOne-STAGE Tip Method for TMT based Proteomic Analysis of Minimal Amount of Cells
LC-MS-based profiling of proteomes with isobaric tag labeling from low-quantity biological and clinical samples, including needle-core biopsies and laser capture microdissection, has been challenging due to limited amount and sample loss during preparation. To address this problem, we developed OnM ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-04-18 | MSV000091734 | MassIVE
ProteomicsKorean Lung Adenocarcinoma proteogenomics
Never-smoker lung adenocarcinoma (NSLA) is prevalent in Asian populations and even more in women. Since epidermal growth factor receptor (EGFR) mutations or anaplastic lymphoma kinase (ALK) fusions are major alterations found in NSLA, studies have focused on NSLA with EGFR and ALK alteration (EA), ...
ORGANISM(S): Homo sapiens (Human) 
2024-03-12 | PXD033360 | Pride
Tmt Lung Korean Proteogenomics Lung cancer 
ProteomicsN-terminome analysis of HeLa cells with UPR stress
N-terminome analysis of HeLa proteome under the stress of unfolded protein response. UPR was derived by combinational treatment of MG132 and thapsigargin. N-terminal enrichment was performed by iNrich method (10.1021/acs.analchem.9b05653). Data was prepared to have duplicates.
ORGANISM(S): Homo sapiens (Human) 
2025-11-10 | PXD058868 | Pride
Human N-terminome Hela Upr 
ProteomicsDistinguishing N-Terminal Methylation from Near-isobaric Modifications by Statistical Analysis of Mass Error Distributions of Fragment Ions
alpha-N-terminal methylation is an understudied post-translational modification with presumed functions involving protein-protein and/or protein-DNA interaction. The covalent addition of mono-, di-, trimethyl groups to free alpha-amino group has proven to be difficult to profile globally by mass spe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-11-14 | MSV000096415 | MassIVE
ProteomicsHuman Glioblastoma Cell Line Secretome LC-MS/MS
To investigate the effect of glioblastoma secretome in activating tau pathology, Glioblastoma cell line secretome were prefractionated with gel filtration chromatography. Secretome analyzed by LC-MS/MS and identified targets using PSM count quantitation.
ORGANISM(S): Homo sapiens (Human) 
2018-07-16 | PXD007969 | Pride
Human Brain Glioblastoma 
ProteomicsQuantitative proteome for C.elegans by 3plex mTRAQ
Vesicle-mediated transport is a fundamental part of the secretory and endocytic pathways. In addition to their role in membrane protein trafficking, Arf-like protein subfamily of small GTPases also plays an important role in development, maintenance of Golgi structure and function. Proper protein tr...
ORGANISM(S): Caenorhabditis elegans 
2022-02-17 | PXD026411 | Pride
C. elegans Mtraq Lc-ms/ms 
ProteomicsPRM of Nt-arginylation under UPR stress
Targeted proteomics of Nt-arginylation on HeLa proteome under the stress of unfolded protein response. UPR was derived by combinational treatment of MG132 and thapsigargin. PRM method was selected to undertake targeted MS2 analysis. Data was prepared to have duplicates.
ORGANISM(S): Homo sapiens (Human) 
2025-11-10 | PXD058872 | Pride
Human Nt-arginylation Hela Upr 
ProteomicsN-terminome Method Development (Discovery)
Developed a method to enrich N-terminome. Several parameters were change to optimization. This project focused on the discovery of N-terminome.
ORGANISM(S): Homo sapiens (Human) 
2020-05-25 | PXD011141 | Pride
Human N-terminome Yeast 
ProteomicsN-terminome Method Development
Developed a method to enrich N-terminome. Several parameters were change to optimization
ORGANISM(S): Homo sapiens (Human) 
2020-05-25 | PXD011117 | Pride
Human N-terminome 
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