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ProteomicsPhosphoproteomic analysis of cell-based resistance to BRAF inhibitor therapy in melanoma
The treatment of melanoma by targeted inhibition of the mutated kinase BRAF with small molecules only temporarily suppresses metastatic disease. In the face of chemical inhibition tumor plasticity, both innate and adaptive, promotes survival through the biochemical and genetic reconfiguration of cel...
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD002079 | Pride
Kinases Phosphoproteomics Braf Drug resistance Mass spectrometry Label free quantitation 
UnknownDevelopment of a tool predicting severity of allergic reaction during peanut challenge.
Not available
S-EPMC6026554 | biostudies-literature
ProteomicsThe choice of search engine for interpretation of immunopeptidomics datasets affects the sequencing depth and the extent of detected HLA allele-specific peptide repertoires
Standardisation of Immunopeptidomics experiments across laboratories is a pressing issue within the field, and currently a variety of different methods for sample preparation and data analysis tools are applied. Here, we compared different software packages commonly used to interrogate immunopeptido...
ORGANISM(S): Homo sapiens (Human) 
2024-08-27 | PXD023202 | Pride
Immunopeptidomics Search engine 
MetabolomicsExtreme genome diversity and cryptic speciation in a harmful algal bloom forming eukaryote

Harmful algal blooms (HABs) of the toxic haptophyte Prymnesium parvum are a recurrent problem in many inland and estuarine waters around the world. Strains of P. parvum vary in the toxins they produce and in other physiological traits associated with HABs, but the genetic basis ...

2023-04-26 | MTBLS5893 | MetaboLights
ProteomicsMapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells
Immunopeptidomic profiling of HLA-DR diverse monocyte-derived dendritic cells pulsed with SARS-CoV-2 spike (S) protein.
ORGANISM(S): Homo sapiens (Human) 
2021-07-09 | PXD021672 | Pride
Sars-cov-2  coronavirus spike protein  receptor binding domain  human leukocyte antigen class ii  hla-ii  peptide presentation  post-translational modification  glycosylation  antigen processing  receptor binding domain  immunopeptidomics 
ProteomicsProteomic analysis of Kveim reagent identifies targets of cellular immunity in sarcoidosis
Kveim-reagent (Kv) skin testing was a historical method of diagnosing sarcoidosis. Intradermal injection of treated sarcoidosis spleen tissue resulted in a granuloma response at injection site by 4-6 weeks. Previous work indicates proteins as the possible trigger of this reaction. We aimed to identi...
ORGANISM(S): Homo sapiens (Human) 
2017-01-31 | PXD005150 | Pride
Interstitial lung diseases Sarcoidosis Immunology Proteomics 
ProteomicsThe choice of search engine affects sequencing depth and HLA allele-specific peptide repertoires.
Standardisation of Immunopeptidomics experiments across laboratories is a pressing issue within the field, and currently a variety of different methods for sample preparation and data analysis tools are applied. Here, we compared different software packages commonly used to interrogate immunopeptido...
ORGANISM(S): Homo sapiens (Human) 
2021-08-10 | PXD025655 | Pride
Search engines Fdr Immunopeptidomics 
UnknownEgg Allergy in US Children.
Not available
S-EPMC7895443 | biostudies-literature
UnknownProgression of follicular lymphoma and related entities: Report from the 2021 SH/EAHP Workshop.
Not available
S-EPMC10233403 | biostudies-literature
UnknownUnderstanding Food-Related Allergic Reactions Through a US National Patient Registry.
Not available
S-EPMC7829042 | biostudies-literature
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