Sort   by:  
 Page size 
ProteomicsParthenolide-treated HeLa cells and purified tubulin
Purified human tubulin treated with parthenolide and HeLa cells treated in vivo with parthenolide
ORGANISM(S): Homo sapiens (Human) 
2021-01-22 | PXD020113 | Pride
Parthenolide Q exactive Tubulin Homo sapiens 
TranscriptomicsTranscription profiling of human primary CD34+ acute myelogenous leukemia specimens obtained from 12 patients treated with 7.5 micromolar parthenolide (PTL)
The effects of 7.5 micromolar parthenolide (PTL) were assessed on primary CD34+ acute myelogenous leukemia specimens obtained from 12 patients. Experiment Overall Design: Acute myelogenous leukemia (AML) specimens were obtained from 12 patients and CD34+ cells were isolated. For each patient, cells...
ORGANISM(S): Homo sapiens 
2008-04-07 | E-GEOD-7538 | biostudies-arrayexpress
GenomicsParthenolide induces ROS-dependent cell death in human gastric cancer cells
Parthenolide induces ROS-dependent cell death in human gastric cancer cells
PRJNA899475 | ENA
TranscriptomicsTreatment of primary acute myelogenous leukemia (AML) specimens with parthenolide (PTL)
The effects of 7.5 micromolar parthenolide (PTL) were assessed on primary CD34+ acute myelogenous leukemia specimens obtained from 12 patients. Keywords: drug response, gene expression search agent
ORGANISM(S): Homo sapiens 
2008-02-27 | GSE7538 | GEO
ProteomicsDesmocollin-1 is associated with pro-metastatic phenotype of luminal A breast cancer cells and is modulated by parthenolide
Desmocollin-1 (DSC1) is a desmosomal transmembrane glycoprotein that maintains cell-to-cell adhesion. DSC1 was previously associated with lymph node metastasis of luminal A breast tumors and was found to increase metastatic potential of MCF7 cells in vitro. To delineate DSC1 role in breast cancer me...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD041029 | Pride
Pulldown Breast cancer Proteomics Dia Dsc1 Metastasis 
GenomicsDesmocollin-1 is associated with pro-metastatic phenotype of luminal A breast cancer cells and is modulated by parthenolide
Desmocollin-1 is associated with pro-metastatic phenotype of luminal A breast cancer cells and is modulated by parthenolide
PRJNA947670 | ENA
UnknownParthenolide Destabilizes Microtubules by Covalently Modifying Tubulin.
Not available
S-EPMC7931505 | biostudies-literature
TranscriptomicsParthenolide induces ROS-dependent cell death in human gastric cancer cells
Parthenolide (PN), a key active ingredient of feverfew, has been used to treat gastrointestinal disorders. However, the mechanism of the cytotoxic effect exerted by PN on tumor cells is not elucidated now. MGC-803 cells treated with and without PN were separately subjected to high throughput RNA seq...
ORGANISM(S): Homo sapiens 
2023-12-31 | GSE217526 | GEO
TranscriptomicsDesmocollin-1 is associated with pro-metastatic phenotype of luminal A breast cancer cells and is modulated by parthenolide
Desmocollin-1 (DSC1) is a desmosomal transmembrane glycoprotein that maintains cell-to-cell adhesion. DSC1 was previously associated with lymph node metastasis of luminal A breast tumors and was found to increase metastatic potential of MCF7 cells in vitro. Therefore, we focused on DSC1 role in cell...
ORGANISM(S): Homo sapiens 
2023-09-06 | GSE228017 | GEO
ProteomicsParthenolide disrupts mitosis by inhibiting ZNF207/BUGZ-promoted kinetochore microtubule attachment
Parthenolide is a natural compound that has shown highly promising anticancer activity. Even though its mode of action has been studied for decades, its antimitotic activity has been largely overlooked, limiting the understanding of its full anticancer potential. In this study, we combined click che...
ORGANISM(S): Homo sapiens (Human) 
2025-05-27 | PXD063178 | Pride
Impact Timstof Lcmsms 
Sort   by:  
 Page size