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Real-time database searching allows for simpler and automated proteomics workflows as it eliminates technical bottlenecks in high throughput experiments. Most importantly, it enables results dependent acquisition (RDA) where search results can be used to guide data acquisition during acquisition. Th...
ORGANISM(S): Homo sapiens (Human) 
2023-03-13 | PXD040716 | Pride
Pseudomonas aeruginosa is a major cause of nosocomial infections and also leads to severe exacerbations in cystic fibrosis or chronic obstructive pulmonary disease. Three intertwined quorum sensing systems control virulence of P. aeruginosa, with the rhl circuit playing the leading role in late and ...
ORGANISM(S): Pseudomonas aeruginosa PA14 
2023-03-11 | PXD038000 | Pride
This project utilized a timsTOF Pro instrument (Bruker) and applied a data independent acquisition (DIA) method, followed by spectral analysis in PaSER (Bruker) to study proteomic changes in the cerebrospinal fluid of sporadic cerebral amyloid angiopathy patients. Results revealed distinct different...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-10-05 | MSV000093046 | MassIVE
This project utilized a timsTOF Pro instrument (Bruker) and applied a data independent acquisition (DIA) method, followed by spectral analysis in PaSER (Bruker) to study proteomic changes in the cerebrospinal fluid of a cerebral amyloid angiopathy pre-clinical model, rTg-DI. Results revealed distinc...
ORGANISM(S): Rattus Norvegicus (ncbitaxon:10116) 
2023-05-26 | MSV000092037 | MassIVE
Minimal residual disease (MRD) status in multiple myeloma (MM) is an important prognostic biomarker. Personalized blood-based targeted mass spectrometry (MS-MRD) detecting M-proteins was shown to provide a sensitive and minimally invasive alternative to MRD assessment in bone marrow. However, MS-MRD...
ORGANISM(S): Homo sapiens (Human) 
2025-06-10 | PXD050329 | Pride
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