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TranscriptomicsMicroarray analysis of Gene expression in limb muscles of three mouse models of Kennedy disease/SBMA
Emerging evidence implicates transcriptional dyseregulation within skeletal muscle in the pathogenesis of Kennedy disease/spinal bulbar muscular atrophy (KD/SBMA). We therefore broadly characterized gene expression in skeletal muscle of three independently generated mouse models of this disorder. Th...
ORGANISM(S): Mus musculus 
2010-10-12 | E-GEOD-10190 | biostudies-arrayexpress
ProteomicsRET Kinase Inhibition in Neuroendocrine Prostate Cancer, part 1
Increased treatment of metastatic castration resistant prostate cancer (mCRPC) with second-generation anti-androgen therapies (ADT) has coincided with a greater incidence of lethal, aggressive variant prostate cancer (AVPC) tumors that have lost androgen receptor (AR) signaling. AVPC tumors may also...
ORGANISM(S): Homo sapiens (Human) 
2020-05-29 | PXD012970 | Pride
Ret Prostate cancer Kinase Phosphoproteomics 
ProteomicsRET Kinase Inhibition in Neuroendocrine Prostate Cancer, part 2
Increased treatment of metastatic castration resistant prostate cancer (mCRPC) with second-generation anti-androgen therapies (ADT) has coincided with a greater incidence of lethal, aggressive variant prostate cancer (AVPC) tumors that have lost androgen receptor (AR) signaling. AVPC tumors may also...
ORGANISM(S): Homo sapiens (Human) 
2020-05-29 | PXD012971 | Pride
Human Kinase Phosphoproteomics Prostate cancer Ret 
no omics definedTranscription profiling of human prostate cancer cells over-expressing androgen receptor following dihydrotestosterone treament
dose and time dependent responses of dihydrotestosterone in androgen receptor over-expressing prostate cancer cells.
ORGANISM(S): Homo sapiens 
2009-10-09 | E-MEXP-2286 | biostudies-arrayexpress
ProteomicsQuantification profiles of enzyme activity, secretion and psychosine levels of Krabbe disease galactosylceramidase missense variants
Krabbe disease (KD) is an autosomal recessive lysosomal storage disorder caused by loss-offunction mutations in the GALC gene, which encodes for the enzyme galactosylceramidase (GALC). GALC is crucial for myelin metabolism. Functional deficiency of GALC leads to toxic accumulation of psychosine, dys...
ORGANISM(S): Homo sapiens (Human) 
2025-05-19 | PXD057472 | Pride
Secretion Missense mutation variant Galactosylceramidase Lysosomal storage disorder Lysosome Galc Psychosine Crispr-cas9 knockout cell Protein trafficking Krabbe disease Expression study Genotype-phenotype correlation Galactosylsphingosine Globoid cell leukodystrophy 
UnknownValidation of the Arabic version of the Muscle Dysmorphic Disorder Inventory (Ar-MDDI) among Lebanese male university students.
Not available
S-EPMC9881329 | biostudies-literature
TranscriptomicsStudy of Cj1501 function in Campylobacter jejuni
In order to study the function of the Campylobacter jejuni Cj1501 gene, a series of experiments were carried out. Three strains were constructed: a Cj1501 knockout strain, a strain where the Cj1501 knockout was complemented in trans, and a strain with a second copy over-expressing Cj1501 from an fdx...
ORGANISM(S): Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 
2012-07-01 | E-GEOD-35016 | biostudies-arrayexpress
Unknown[18F]-FDHT PET/CT as a tool for imaging androgen receptor expression in high-grade glioma.
Not available
S-EPMC7954111 | biostudies-literature
TranscriptomicsGlobal gene expression analysis of the phytopathogen Xylella fastidiosa at high iron availability
Xylella fastidiosa is the etiologic agent of a wide range of plant diseases including citrus variegated chlorosis (CVC), a major threat to the Brazilian citrus industry. Genome sequences of several strains of this phytopathogen are accessible, enabling large-scale functional studies. Transcript leve...
ORGANISM(S): Xylella fastidiosa 
2007-09-01 | E-GEOD-5886 | biostudies-arrayexpress
UnknownAssociations between single-question Visual Analogue Scale pain score and weight-bearing and non-weight-bearing domains of Western Ontario and McMaster Universities Arthritis Index pain: data from 2 phase 3 clinical trials.
Not available
S-EPMC9529038 | biostudies-literature
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