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Using a systematic proteomic approach, we define the protein-protein interaction network for PLD superfamily and phosphatidic acid in human cells and reveal diverse cellular signaling events involved for this key protein family and lipid.
ORGANISM(S): Homo sapiens (Human) 
2022-01-16 | PXD029183 | Pride
Plants both lose water and take in carbon dioxide through microscopic stomatal pores, each of which is regulated by a surrounding pair of guard cells. During drought, the plant hormone abscisic acid (ABA) inhibits stomatal opening and promotes stomatal closure, thereby promoting water conservation. ...
au10-12_pa - phosphatidic acid in gene expression - Role of DGK in gene expression - Compounds were added 4h before cell harvesting. 6 dye-swap - treated vs untreated comparison
ORGANISM(S): Arabidopsis thaliana 
au10-12_pa - phosphatidic acid in gene expression - Role of DGK in gene expression - Compounds were added 4h before cell harvesting.
ORGANISM(S): Arabidopsis thaliana 
2012-03-01 | GSE35872 | GEO
Disturbed intramitochondrial phosphatidic acid transport impairs cellular stress signaling
A phosphatidic acid-based retrograde signaling pathway responsive to abiotic stress in Arabidopsis.
phosphatidic acid in gene expression-Phosphatidic acid in gene expression
Double membrane vesicles (DMVs) are used as replication organelles by pathogenic RNA viruses such as hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Viral DMVs are morphologically analogous to DMVs formed during autophagy, and although the proteins required...
ORGANISM(S): Homo sapiens (Human) 
2022-01-24 | PXD029692 | Pride
Lipid transfer proteins of the Ups1/PRELID1 family facilitate the transport of phospholipids across the intermembrane space of mitochondria in a lipid-specific manner. Heterodimeric complexes of yeast Ups1/Mdm35 or human PRELID1/TRIAP1 shuttle phosphatidic acid (PA) synthesized in the endoplasmic re...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-01-22 | PXD022321 | Pride
A natural ZmDGK4 allele accelerates maize grain dehydration via ER-localized phosphatidic acid signaling
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