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Using a systematic proteomic approach, we define the protein-protein interaction network for PLD superfamily and phosphatidic acid in human cells and reveal diverse cellular signaling events involved for this key protein family and lipid.
ORGANISM(S): Homo sapiens (Human) 
2022-01-16 | PXD029183 | Pride
au10-12_pa - phosphatidic acid in gene expression - Role of DGK in gene expression - Compounds were added 4h before cell harvesting. 6 dye-swap - treated vs untreated comparison
ORGANISM(S): Arabidopsis thaliana 
au10-12_pa - phosphatidic acid in gene expression - Role of DGK in gene expression - Compounds were added 4h before cell harvesting.
ORGANISM(S): Arabidopsis thaliana 
2012-03-01 | GSE35872 | GEO
Disturbed intramitochondrial phosphatidic acid transport impairs cellular stress signaling
A phosphatidic acid-based retrograde signaling pathway responsive to abiotic stress in Arabidopsis.
phosphatidic acid in gene expression-Phosphatidic acid in gene expression
Double membrane vesicles (DMVs) are used as replication organelles by pathogenic RNA viruses such as hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Viral DMVs are morphologically analogous to DMVs formed during autophagy, and although the proteins required...
ORGANISM(S): Homo sapiens (Human) 
2022-01-24 | PXD029692 | Pride
A natural ZmDGK4 allele accelerates maize grain dehydration via ER-localized phosphatidic acid signaling
Cellular lipid metabolism is subject to strong homeostatic regulation, but players involved in and mechanisms underlying these pathways remain mostly uncharacterized. Here, we develop and exploit a “Feeding-Fishing” approach coupling membrane editing using optogenetic lipid-modifying enzymes (feedin...
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD070378 | Pride
Plants depend on photosynthesis as their primary means to generate energy and building blocks, and adverse environmental conditions can stress the photosynthetic apparatus leading to the production of toxic byproducts. In the long term, stress experienced by the chloroplast must be communicated to t...
ORGANISM(S): Arabidopsis thaliana 
2026-03-31 | GSE319128 | GEO
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