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ProteomicsPhospho enrichement in exponential and starvation condition
Phospho enrichement in exponential and starvation condition
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-06-20 | PXD059338 | Pride
Phospho enrichement 
ProteomicsEfficient removal of TMT-labelling by-products in proteomic samples by methylamine  
Comparing the performance of methylamine and hydroxylamine on phospho-peptide analysis, particularly in relation to the identification of more complex dose-dependent patterns.
ORGANISM(S): Homo sapiens (Human) 
2025-03-17 | PXD056908 | Pride
Proteomics Over-labelling Tmt-labeling Phosphoproteomics 
ProteomicsProteomic and phosphoproteomic characterization of cardiovascular dysfunction arising from exposure to space radiation
Mice were exposed to 150 cGy Galactic Cosmic Ray (GCR) versus sham, and hearts and plasma were harvested at 8 months post radiation. Hearts were homogenized in 5% SDS and 250 ugs protein was digested with trypsin using an S-trap followed by TMT labeling, high-pH reversed-phase fractionation and phos...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-07-10 | MSV000092395 | MassIVE
Proteomics(Phospho-)proteomic analysis of gemcitabine resistant pancreatic cancer cells reveals that microtubule-associated protein 2 upregulation associates with taxane treatment response
Chemoresistance hampers the treatment of patients suffering from pancreatic ductal adenocarcinoma (PDAC). The present study aimed to evaluate the proteome and phosphoproteome of gemcitabine-sensitive and -resistant PDAC cells to identify novel targets and predictive biomarkers.The oncogenic capabili...
ORGANISM(S): Homo sapiens (Human) 
2019-06-19 | PXD010112 | Pride
Human Single-shot Paclitaxel Label-free Phosphoproteomics Pancreatic cancer Gemcitabine 
ProteomicsPhosphoproteomic Profiling of T-Cell Acute Lymphoblastic Leukemia Identifies Targetable Kinases and Combination Treatments
Protein kinase inhibitors are amongst the most successful cancer treatments, but targetable kinases activated by gene fusions are rare in T-ALL (e.g., NUP214-ABL1). Nevertheless, leukemic blasts rely on enhanced kinase signaling to sustain dysregulated proliferation. Protein kinases can be hyper-act...
ORGANISM(S): Homo sapiens (Human) 
2022-02-21 | PXD024807 | Pride
Human Single-shot T-all Ptyr Label-free Phosphoproteomics T-cell acute lymphoblastic leukemia 
ProteomicsFeasibility of phosphoproteomics on left-over sample after RNA extraction (RNA-Bee)
In daily practice biomolecules are usually extracted with their own specific protocols for downstream omics analysis. However, when sample material is limited, an all-in-one strategy is preferable. DNA, RNA and proteins can be isolated with phenol guanidine thiocyanate based extraction, yet lysis wi...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2021-04-22 | PXD023665 | Pride
Phenol guanidine thiocyanate Tissue Lysis Rnab Phosphoproteomics Cell line 
TranscriptomicsImmunological Genome Project data Phase 1
Gene-expression microarray datasets generated as part of the Immunological Genome Project (ImmGen). Primary cells from multiple immune lineages are isolated ex-vivo, primarily from young adult B6 male mice, and double-sorted to >99% purity. RNA is extracted from cells in a centralized manner, amplif...
ORGANISM(S): Mus musculus 
2009-05-02 | E-GEOD-15907 | biostudies-arrayexpress
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