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Transcriptomicsm6A RNA methylation promotes XIST-mediated transcriptional repression
XIST is a long non-coding RNA (lncRNA) that mediates transcriptional silencing of X chromosome genes. Here we show that XIST is highly methylated with at least 78 N6-methyladenosine (m6A) residues, a reversible base modification whose function in lncRNAs is unknown. We show that m6A formation in XIS...
ORGANISM(S): Homo sapiens 
2016-09-07 | E-GEOD-78030 | biostudies-arrayexpress
Proteomics,MultiomicsAPOBEC3A is an Oral Cancer Prognostic Biomarker in Taiwanese Carriers of an APOBEC Deletion Polymorphism
Chen T-W, Lee C-C, Liu H, Wu C-S, Pickering CR, Huang P-J, et al., Nature Communications 8, Article number: 465 (2017) doi:10.1038/s41467-017-00493-9

Oral squamous cell carcinoma is a prominent cancer worldwide, p...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-08-28 | MSV000084250 | MassIVE
ProteomicsIdentifying candidate protein markers of acute kidney injury in acute decompensated heart failure using sheep kidney cortex
A quarter of patients with acute decompensated heart failure (ADHF) experience acute kidney injury (AKI), an abrupt loss of kidney function that doubles the risk of death at one-year. There is a critical need to identify early markers for AKI in ADHF, however, no protein candidates have been validat...
ORGANISM(S): Ovis aries 
2022-01-19 | PXD028983 | Pride
Adhf Kidney Sheep Swath-ms Tripletof Acute kidney injury 
ProteomicsComparison of SPEED, S-Trap, and In-Solution based sample preparation methods for tandem mass spectrometry
Bottom-up proteomic analyses rely on efficient protein extraction from tissue and proteolysis into peptides for mass spectrometry. Commonly used detergent-based strategies aid cell lysis and protein solubilization but are poorly compatible with downstream protein digestion and liquid chromatography-...
ORGANISM(S): Ovis aries 
2023-03-30 | PXD030796 | Pride
Speed Plasma Kidney Sheep Swath-ms Tripletof S-trap 
ProteomicsComparison of SPEED, S-Trap, and In-Solution based sample preparation methods for tandem mass spectrometry
Bottom-up proteomic analyses rely on efficient protein extraction from tissue and proteolysis into peptides for mass spectrometry. Commonly used detergent-based strategies aid cell lysis and protein solubilization but are poorly compatible with downstream protein digestion and liquid chromatography-...
ORGANISM(S): Ovis aries 
2023-03-30 | PXD030797 | Pride
Speed Plasma Kidney Sheep Tripletof S-trap Dda 
UnknownIdentifying Candidate Protein Markers of Acute Kidney Injury in Acute Decompensated Heart Failure.
Not available
S-EPMC8778509 | biostudies-literature
UnknownFc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors.
Not available
S-EPMC5437702 | biostudies-literature
UnknownA glucose meter interface for point-of-care gene circuit-based diagnostics.
Not available
S-EPMC7851131 | biostudies-literature
UnknownVoter information campaigns and political accountability: Cumulative findings from a preregistered meta-analysis of coordinated trials.
Not available
S-EPMC6609214 | biostudies-literature
UnknownCharacterization of Ebola Virus Risk to Bedside Providers in an Intensive Care Environment.
Not available
S-EPMC7996731 | biostudies-literature
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