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ProteomicsScaling of cellular processes with ploidy
While most eukaryotic cells are diploid, with two chromosome sets, variances in ploidy are common. Despite the relative prevalence of ploidy changes and their relevance for pathology and evolution, a complete picture of consequences of altered ploidy is missing. We analyzed transcriptome and proteom...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-08-15 | PXD022605 | Pride
Lc-msms Yeast Silac Ploidy 
TranscriptomicsSingle-nucleus RNA-seq of liver tissue of 3 months old mice to investigate crosstalk between ploidy and zonation
Single-nucleus RNA-seq-2 method that allows deep characterization of nuclei isolated from frozen archived tissues. We have used this approach to characterize the transcriptional profile of individual hepatocytes with different levels of ploidy. This method has the potential to explore archived sampl...
ORGANISM(S): Mus musculus 
2021-05-06 | E-MTAB-10223 | biostudies-arrayexpress
TranscriptomicsSingle-nucleus RNA-seq2 of liver tissue of 3 months old mice to investigate crosstalk between ploidy and zonation
Single-nucleus RNA-seq-2 method that allows deep characterization of nuclei isolated from frozen archived tissues. We have used this approach to characterize the transcriptional profile of individual hepatocytes with different levels of ploidy. This method has the potential to explore archived sampl...
ORGANISM(S): Mus musculus 
2021-05-06 | E-MTAB-9333 | biostudies-arrayexpress
GenomicsScaling of cellular gene expression with ploidy
Scaling of cellular gene expression with ploidy
PRJNA682117 | ENA
GenomicsCell integrity limits ploidy in budding yeast
Cell integrity limits ploidy in budding yeast
PRJNA1150212 | ENA
ProteomicsEffect of ploidy on Salmon physiology - Liver
This study investigated firstly, the impact of ploidy on growth performance and whole body composition of Atlantic salmon at different early freshwater stages (34 dph (days post-hatching) alevin; 109 dph; fry and 162 dph parr;) and secondly, whether phenotypic differences at these stages were reflec...
ORGANISM(S): Salmo salar (Atlantic salmon) 
2017-12-14 | PXD005450 | Pride
Salmon Ploidy Liver 
ProteomicsPhosphoproteomic analysis identifies supervillin as a new ERK3 substrate regulating cytokinesis and ploidy of breast cancer cells
Extracellular signal-regulated kinase 3 (ERK3) is a poorly characterized member of the mitogen-activated protein (MAP) kinase family. Functional analysis of the ERK3 signaling pathway has been hampered by a lack of knowledge about the substrates and downstream effectors of the kinase. Here, we used ...
ORGANISM(S): Homo sapiens (Human) 
2023-02-21 | PXD028061 | Pride
Breast cancer Cytokinesis Supervillin Erk3 Ploidy Phosphoprotoemic 
ProteomicsEffect of ploidy on Salmon physiology - Whole fish larvae
This study investigated firstly, the impact of ploidy on growth performance and whole body composition of Atlantic salmon at different early freshwater stages (34 dph (days post-hatching) alevin; 109 dph; fry and 162 dph parr;) and secondly, whether phenotypic differences at these stages were reflec...
ORGANISM(S): Salmo salar (Atlantic salmon) 
2017-12-14 | PXD005452 | Pride
Salmon Larvae Ploidy 
ProteomicsEffect of ploidy on Salmon physiology - White muscle
This study investigated firstly, the impact of ploidy on growth performance and whole body composition of Atlantic salmon at different early freshwater stages (34 dph (days post-hatching) alevin; 109 dph; fry and 162 dph parr;) and secondly, whether phenotypic differences at these stages were reflec...
ORGANISM(S): Salmo salar (Atlantic salmon) 
2017-12-14 | PXD005451 | Pride
Muscle Salmon Ploidy 
TranscriptomicsIdentification of ploidy-regulated genes in budding yeast
Using RNA-seq, we analyzed the transcriptomes of isogenic haploid (MATa) and tetraploid (MATaaaa) budding yeast strains in the Sigma 1278b background and identified genes whose regulation was altered by ploidy. Analysis of poly(A)+ RNA from 2 biological replicates of haploid (MATa) and tetraploid (M...
ORGANISM(S): Saccharomyces cerevisiae 
2010-11-04 | E-GEOD-19685 | biostudies-arrayexpress
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