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ProteomicsVulvar squamous cell carcinoma aggressiveness associated with differential expression of collagen and STAT1
Background: Vulvar squamous cell carcinoma (vSCC) is a rare but debilitating disease. One vSCC subtype comprises tumor cells that grow and expand as a cohesive sheet of cells that “pushes” and compresses the associated lymphoplasmacytic (LPC) stroma. Another vSCC subtype features tumor cells that gr...
ORGANISM(S): Homo sapiens (Human) 
2017-12-12 | PXD006901 | Pride
Human Stroma immune Ffpe tissue Cytokine Cell adhesion 
ProteomicsAlzheimer’s Disease (AD) and Lewy Body Dementia (LBD): Detection of S-Nitrosylation in Key Proteins in Human, Post-mortem Brain Samples
FAD and Lewy Body Dementia (LBD): Detection of S-Nitrosylation in Key Proteins in Human, Post-mortem Brain Samples
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD020945 | Pride
Lbd Ad Lc-ms2 
UnknownEffect of Inpatient Palliative Care During Hematopoietic Stem-Cell Transplant on Psychological Distress 6 Months After Transplant: Results of a Randomized Clinical Trial.
Not available
S-EPMC5675739 | biostudies-literature
ProteomicsNext-Generation Multiplexed Targeted Proteomics Quantifies Post-Translational Modifications, Compound-Protein Interactions, and Disease Biomarkers with High Throughput
The GoDig platform enables sensitive, multiplexed targeted pathway proteomics without manual scheduling or synthetic standards. Here we present GoDig 2.0, which increases sample multiplexing to 35-fold, improves time efficiency and reduces scan delays for higher success rates, and allows flexible sp...
ORGANISM(S): Homo sapiens (Human) 
2026-06-25 | PXD065227 | Pride
Abpp Sample multiplexing Ptms Targeted proteomics Tmt Ubiquitylomics Reactive cysteines Phosphoproteomics Godig 
TranscriptomicsGene expression data from precision cut human liver slices treated to diclofenac
Drug-induced liver injury (DILI) is an important clinical problem. Here we used a genomics approach to establish the critical drug-induced toxicity pathways that act in synergy with the pro-inflammatory cytokine tumor necrosis factor (TNF) to cause cell death of liver HepG2 cells. Transcriptomics o...
ORGANISM(S): Homo sapiens 
2014-01-22 | E-GEOD-54255 | biostudies-arrayexpress
ProteomicsS-nitrosation of proteins relevant to Alzheimer’s disease during early stages of neurodegeneration
Protein S-nitrosation (SNO-protein) is a post-translational modification in which a cysteine (Cys) residue is modified by nitric oxide (SNO-Cys). SNO-proteins impact many biological systems, but their identification has been technically challenging. We developed a chemical proteomic strategy - SNOTR...
ORGANISM(S): Mus musculus (Mouse) 
2016-03-31 | PXD003802 | Pride
S-nitrosylation Alzheimer's disease Neurodegeneration 
TranscriptomicsDe novo kidney transplantation without use of calcineurin inhibitors preserves renal structure and function
Background: Despite significant improvements in short-term kidney transplant survival, comparable increases in 5 and 10-year outcomes have not been achieved. Chronic allograft nephropathy (CAN) is a major cause of late graft loss. Toxic nephropathy and inadequate long-term immunosuppression are poss...
ORGANISM(S): Homo sapiens 
2004-09-23 | E-GEOD-1743 | biostudies-arrayexpress
TranscriptomicsExpression data from human hepatocellular carcinoma cell line HepG2
Drug-induced liver injury (DILI) is an important clinical problem. Here we used a genomics approach to establish the critical drug-induced toxicity pathways that act in synergy with the pro-inflammatory cytokine tumor necrosis factor (TNF) to cause cell death of liver HepG2 cells. Transcriptomics of...
ORGANISM(S): Homo sapiens 
2014-01-22 | E-GEOD-54254 | biostudies-arrayexpress
TranscriptomicsExpression data from primary mouse hepatocytes treated with Diclofenac
Drug-induced liver injury (DILI) is an important clinical problem. Here we used a genomics approach to establish the critical drug-induced toxicity pathways that act in synergy with the pro-inflammatory cytokine tumor necrosis factor M-oM-^AM-! (TNFM-oM-^AM-!) to cause cell death of liver HepG2 cell...
ORGANISM(S): Mus musculus 
2014-01-22 | E-GEOD-54256 | biostudies-arrayexpress
UnknownHigh-dose vincristine sulfate liposome injection for advanced, relapsed, and refractory adult Philadelphia chromosome-negative acute lymphoblastic leukemia.
Not available
S-EPMC4979201 | biostudies-literature
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