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ProteomicsEnhancing tandem MS sensitivity and peptide identification via ion pre-accumulation in an Orbitrap mass spectrometer
High-throughput mass spectrometry-based proteomics is gaining increasing interest, but mass spectrometers need to adapt to enable faster analysis times. For Orbitrap mass spectrometers, faster scan rates are constrained by limitations on ion accumulation time, duty cycle, and transient length. Here,...
ORGANISM(S): Homo sapiens (Human) 
2026-02-16 | PXD061135 | Pride
Lc-ms Dia Pre-accumulation Proteomics Dda 
ProteomicsHigher-Throughput Proteome Profiling Enabled by Parallelized Pre-Accumulation and Optimized Ion Processing in the Orbitrap Astral Zoom Mass Spectrometer-Features-90spd
High-throughput proteomics is critical for understanding biological processes, enabling large-scale studies such as biomarker discovery and systems biology. However, current mass spectrometry technologies face limitations in speed, sensitivity, and scalability for analyzing large sample cohorts. The...
ORGANISM(S): Homo sapiens (Human) 
2026-02-13 | PXD066925 | Pride
Orbitrap astral zoom Peak deconcolution Pre/accumulation Higher acquisition speed 
ProteomicsHigher-Throughput Proteome Profiling Enabled by Parallelized Pre-Accumulation and Optimized Ion Processing in the Orbitrap Astral Zoom Mass Spectrometer -fractionation
High-throughput proteomics is critical for understanding biological processes, enabling large-scale studies such as biomarker discovery and systems biology. However, current mass spectrometry technologies face limitations in speed, sensitivity, and scalability for analyzing large sample cohorts. The...
ORGANISM(S): Homo sapiens (Human) 
2026-02-16 | PXD066659 | Pride
Hph fractionation Orbitrap astral zoom 
ProteomicsHigher-Throughput Proteome Profiling Enabled by Parallelized Pre-Accumulation and Optimized Ion Processing in the Orbitrap Astral Zoom Mass Spectrometer-Quantitation
High-throughput proteomics is critical for understanding biological processes, enabling large-scale studies such as biomarker discovery and systems biology. However, current mass spectrometry technologies face limitations in speed, sensitivity, and scalability for analyzing large sample cohorts. The...
ORGANISM(S): Homo sapiens (Human) Escherichia coli Saccharomyces cerevisiae (Baker's yeast) 
2026-02-16 | PXD066672 | Pride
Orbitrap astral zoom Three species mix 
ProteomicsHigher-Throughput Proteome Profiling Enabled by Parallelized Pre-Accumulation and Optimized Ion Processing in the Orbitrap Astral Zoom Mass Spectrometer -50SPD-100ng
High-throughput proteomics is critical for understanding biological processes, enabling large-scale studies such as biomarker discovery and systems biology. However, current mass spectrometry technologies face limitations in speed, sensitivity, and scalability for analyzing large sample cohorts. The...
ORGANISM(S): Homo sapiens (Human) 
2026-02-16 | PXD067317 | Pride
50spd feature tritation 100ng Orbitrap astral zoom 
ProteomicsHigher-Throughput Proteome Profiling Enabled by Parallelized Pre-Accumulation and Optimized Ion Processing in the Orbitrap Astral Zoom Mass Spectrometer -50SPD-250ng
High-throughput proteomics is critical for understanding biological processes, enabling large-scale studies such as biomarker discovery and systems biology. However, current mass spectrometry technologies face limitations in speed, sensitivity, and scalability for analyzing large sample cohorts. The...
ORGANISM(S): Homo sapiens (Human) 
2026-02-13 | PXD067363 | Pride
50spd feature tritation Orbitrap astral zoom 
ProteomicsHigher-Throughput Proteome Profiling Enabled by Parallelized Pre-Accumulation and Optimized Ion Processing in the Orbitrap Astral Zoom Mass Spectrometer-Cell lines
High-throughput proteomics is critical for understanding biological processes, enabling large-scale studies such as biomarker discovery and systems biology. However, current mass spectrometry technologies face limitations in speed, sensitivity, and scalability for analyzing large sample cohorts. The...
ORGANISM(S): Homo sapiens (Human) 
2026-02-06 | PXD066686 | Pride
Orbitrap astral zoom Hph fractionation 
ProteomicsHigher-Throughput Proteome Profiling Enabled by Parallelized Pre-Accumulation and Optimized Ion Processing in the Orbitrap Astral Zoom Mass Spectrometer-DDA-DIA
High-throughput proteomics is critical for understanding biological processes, enabling large-scale studies such as biomarker discovery and systems biology. However, current mass spectrometry technologies face limitations in speed, sensitivity, and scalability for analyzing large sample cohorts. The...
ORGANISM(S): Homo sapiens (Human) 
2026-02-16 | PXD066944 | Pride
Dda Dia Orbitral astral zoom 
ProteomicsHigher-Throughput Proteome Profiling Enabled by Parallelized Pre-Accumulation and Optimized Ion Processing in the Orbitrap Astral Zoom Mass Spectrometer – REVISION
High-throughput proteomics is critical for understanding biological processes, enabling large-scale studies such as biomarker discovery and systems biology. However, current mass spectrometry technologies face limitations in speed, sensitivity, and scalability for analyzing large sample cohorts. The...
ORGANISM(S): Homo sapiens (Human) Escherichia coli Saccharomyces cerevisiae (Baker's yeast) 
2026-01-26 | PXD071972 | Pride
Astral Ms Orbitrap Zoom 
TranscriptomicsDisplacement and re-accumulation of centromeric cohesin during transient pre-anaphase centromere splitting
The ring-shaped cohesin complex links sister chromatids until their timely segregation during mitosis. Cohesin is enriched at centromeres, where it provides the cohesive counter-force to bi-polar tension produced by the mitotic spindle. As a consequence of spindle tension, centromeric sequences tran...
ORGANISM(S): Saccharomyces cerevisiae 
2007-09-29 | E-GEOD-8661 | biostudies-arrayexpress
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