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Proteome wide protein quantification has become facile in the last years supported by label-free discovery proteomics approaches and powerful, easy to use software. We set out to independently evaluate this highly peptide centric technology focusing on the performance of some of the currently most p...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2017-03-07 | PXD004025 | Pride
Treatment of multiple myeloma (MM) with the second-generation proteasome inhibitor (PI) carfilzomib (CFZ) is associated with higher incidence of cardiovascular adverse events compared to first-generation PI bortezomib (BTZ). CFZ and BTZ inhibit the individual proteasome subunits beta1, beta2 and bet...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-01 | PXD029077 | Pride
The project aimed to determine proteomics changes in decidua from patients suffering from unexplained early recurrent pregnancy loss (RPL) compared to women undergoing elective abortions. Comparative proteomics analysis by label-free data-independent LC-MS/MS was performed on fresh frozen decidua ti...
ORGANISM(S): Homo sapiens (Human) 
2024-06-12 | PXD048340 | Pride
The project aimed to determine proteomics changes in Bladder cancer (BCa) tissue from early to more advanced stages of the disease and identify the proteins associated with the progression. The samples used in this study were fresh frozen BCa tissues from patients collected immediately after surgery...
ORGANISM(S): Homo sapiens (Human) 
2023-10-22 | PXD044432 | Pride
The project aimed to determine proteomics changes in chorionic villi from patients suffering from unexplained early recurrent pregnancy loss (RPL) compared to women undergoing elective abortions. Comparative proteomics analysis by label-free data-independent LC-MS/MS was performed on fresh frozen ch...
ORGANISM(S): Homo sapiens (Human) 
2024-08-27 | PXD048344 | Pride
Salt stress is a rising threat to agriculture system. The accumulation of salts near the plant roots hampers the normal uptake of water causing osmotic stress and ionic toxicity to the plant. Thompson Seedless is a popular table grape variety of Vitis vinifera L., which is sensitive to salt stress w...
ORGANISM(S): Vitis vinifera (Grape) 
2020-01-27 | PXD015515 | Pride
The holistic nature of omics studies makes them ideally suited to generate hypotheses on health and disease. Sequencing-based genomics and mass spectrometry (MS)-based proteomics are linked through epigenetic regulation mechanisms. However, epigenomics is currently focused on DNA methylation status ...
ORGANISM(S): Homo Sapiens 
2022-02-11 | PXD031500 | panorama
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