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ProteomicsSalivary biomarkers of diabetic retinopathy, part 1
To characterize human salivary proteome and determine changes in proteins expression in different stages of diabetic retinopathy.
ORGANISM(S): Homo sapiens (Human) 
2016-04-26 | PXD003723 | Pride
Human Type-2diabetes mellitus Saliva Diabetic retinopathy 
Genomicsgut microbiome of proliferative diabetic retinopathy
gut microbiome of proliferative diabetic retinopathy Metagenome
PRJNA753622 | ENA
ProteomicsDifferences in Aqueous Humor Protein Profiles in Patients With Proliferative Diabetic Retinopathy Before and After Aflibercept Treatment
To investigate the changes in aqueous humor (AH) protein profiles before and after intravitreal aflibercept (IVA) treatment in patients with proliferative diabetic retinopathy (PDR) patients. 5 PDR patients provided 10 samples of AH before and after IVA treatment (pre-group vs post-group). Proteins ...
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD039210 | Pride
Proteomics Aflibercept Proliferative diabetic retinopathy Lc-ms/ms 
ProteomicsSerum Disease-specific IgG Fc Glycosylation as Potential Biomarkers for Nonproliferative and Proliferative Diabetic Retinopathy Using Mass Spectrometry
The patients were enrolled and categorized into three groups according to clinical diagnosis: non-diabetic retinopathy; nonproliferative diabetic retinopathy ; and proliferative diabetic retinopathy. Gel electrophoresis was performed to separate IgG from morning fasting blood samples and polyaniline...
ORGANISM(S): Homo sapiens (Human) 
2025-06-16 | PXD057612 | Pride
Igg n-glycosylation Mass spectrometry Biomarkers. Diabetic retinopathy 
TranscriptomicsGene Expression Profile of Fibrovascular Membrane Associated with Proliferative Diabetic Retinopathy
Proliferative diabetic retinopathy (PDR) is a vision-threatening disorder characterized by the formation of cicatricial fibrovascular membranes leading to traction retinal detachment. Despite the recent advance in the treatment of PDR such as vitreoretinal surgery with use of anti-vascular endotheli...
ORGANISM(S): Homo sapiens 
2014-08-16 | E-GEOD-60436 | biostudies-arrayexpress
GenomicsVitreous of proliferative diabetic retinopathy patients
Vitreous of proliferative diabetic retinopathy patients
PRJNA790455 | ENA
ProteomicsPutative tear fluid biomarkers of diabetic retinopathy
Identification of tear fluid biomarkers may offer a non-invasive strategy for detecting diabetic patients with increased risk of developing diabetic retinopathy (DR) or increased disease progression, thus helping both improving diagnostic accuracy and understanding the pathophysiology of the disease...
ORGANISM(S): Homo sapiens (Human) 
2022-05-31 | PXD033101 | Pride
Human Lc-msms Type 2 diabetes Proliferative diabetic retinopathy Nonproliferative diabetic retinopathy Tear fluid 
ProteomicsHuman PDR Vitreous Variability Study, TMT-MS
Control (n=27) and proliferative diabetic retinopathy (n=23) vitreous samples were treated as biologically distinct individuals or pooled together and aliquoted into technical replicates. Quantitative mass spectrometry with tandem mass tag labeling was used to identify proteins in individual or pool...
ORGANISM(S): Homo sapiens (Human) 
2022-02-14 | PXD025986 | Pride
Proliferative diabetic retinopathy Vitreous Tmt-ms Human 
ProteomicsProteomics of Vitreous Humor Reveals Upstream Regulators of Proliferative Diabetic Retinopathy
To investigate the key regulators of the disease by comparing the abundance of vitreous proteins between the patients with proliferative diabetic retinopathy (PDR) and the controls with idiopathic epiretinal membrane (iERM).
ORGANISM(S): Homo Sapiens 
2021-07-26 | PXD027556 |
ProteomicsProtein profile analysis of 12 human vitreous samples using labelfree method
To study the differences in protein profiles before and after intravitreal ranibizumab (IVR) treatment, 12 vitreous humor (VH) samples were collected from 6 proliferative diabetic retinopathy (PDR) patients before (pre group) and after IVR treatment (post group). LC–MS/MS and bioinformatics analysis...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD027592 | Pride
Proliferative diabetic retinopathy  proteomics  ranibizumab  label-free  lc–ms/ms  prm 
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