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ProteomicsProtein corona formation on nanoplastics: polystyrene and PVC
In this study, the proteins forming the protein corona on PS and PVC were investigated after 5 min, 1 h, 6 h, or 24 h incubation of the nanoplastics with human plasma. TMT-based untargeted proteomics were applied to identify the proteins forming the protein corona.
ORGANISM(S): Homo sapiens (Human) 
2024-10-25 | PXD032162 | Pride
Protein corona Pvc Ps Tmt Nanoplastics Human 
ProteomicsToxicity of true-to-life microplastics to human induced pluripotent stem cell -derived intestinal epithelia correlates to their protein corona composition
This study was conducted to determine the composition of the protein corona formed in cell culture medium on product-derived true-to-life microplastics and to link the functions of the protein corona to biological effects of true-to-life microplastics.
ORGANISM(S): Bos taurus (Bovine) 
2026-01-05 | PXD061584 | Pride
Micro and nanoplastics  protein corona  stem cells  intestine  hazard ranking  human  toxicology 
ProteomicsAn environmental ecocorona influences the formation and evolution of the biological corona on the surface of single-walled carbon nanotubes - proteome
In this study, the formation of a protein corona on two different SWCNTs under presence or absence of an ecocorona was investigated at four different time points.
ORGANISM(S): Cyprinus carpio (Common carp) 
2021-04-14 | PXD022788 | Pride
Protein corona Carp Swcnts 
ProteomicsEstablishment and clinical application evaluations of a deep mining strategy of plasma proteomics based on nanomaterial protein coronas
In this study, a deep mining strategy of plasma proteomics was established by combing the protein corona formed by deep mining beads (DMB beads, hereafter referred to as magnetic covalent organic frameworks Fe3O4@TpPa-1), DIA-MS detection and the DIA-NN library searching method.
ORGANISM(S): Homo Sapiens 
2023-05-31 | PXD042554 |
ProteomicsNano-omics Enables Plasma-to-Tumour Tissue Integrated Proteomics for Biomarker Discovery in Glioblastoma
The dismal survival of patients with glioblastoma (GB) has only marginally improved over the past two decades, underscoring the urgent need for new technologies to advance early detection and disease monitoring strategies. Despite the promise of 'liquid biopsies’, no blood-based biomarkers have yet ...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-03-11 | PXD060393 | Pride
Protein corona Proteomics Neuro-oncology Early detection Liquid-biopsy Brain cancer Biomarkers 
ProteomicsA farnesyl-dependent structural role for CENP-E in expansion of the fibrous corona
Correct chromosome segregation during cell division depends on proper connections between spindle microtubules and kinetochores. During prometaphase, kinetochores are temporarily covered with a dense protein meshwork known as the fibrous corona. Formed by oligomerization of ROD/ZW10/ZWILCH-SPINDLY (...
ORGANISM(S): Homo sapiens (Human) 
2023-10-09 | PXD040338 | Pride
Cenp-e Farnesylation Kinetochores Chromosome segregation Rod/zw10/zwilch-spindly (rzz-s) complex 
ProteomicsHuman whole blood and plasma from healthy participants comparing VAMS optimised sample preparation methods to other conventional methods.
Whole blood and plasma samples from healthy volunteers were processed using our novel VAMS-optimised technique involving selective washing steps to deplete high-abundance proteins. Samples were analysed using shotgun liquid chromatography mass spectrometry with data-independent acquisition (DIA) mod...
ORGANISM(S): Homo sapiens (Human) 
2025-12-24 | PXD065732 | Pride
Human Plasma Vams Anticoagulants Whole blood Storage Protein corona beads 
ProteomicsBenchmarking plasma from clinical and preclinical models
The push for new clinical biomarkers has seen rapid innovation in biofluid analysis, particularly for plasma. For mass-spectrometry (MS)-based analysis, achieving depth and quantitative accuracy whilst ensuring throughput continues to shape plasma methods development. Numerous workflows have emerged...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2026-07-27 | PXD072131 | Pride
Human Dia Serum Plasma Rat Orbitrap astral 
ProteomicsSupervised learning predicts the in vivo fate of engineered nanomaterials
Despite having exquisite control over nanoparticle design, controlling nanoparticle fate in vivo remains a major barrier for clinical translation. This is because we do not understand how nanoparticles interact with the surrounding environment in vivo and how this lack of control contributes towards...
ORGANISM(S): Mus musculus (Mouse) 
2024-09-14 | PXD011354 | Pride
Nanoparticles Protein corona Mass spectrometry Neural networks Predictive biology 
UnknownTime course of the sensitivity and specificity of anti-SARS-CoV-2 IgM and IgG antibodies for symptomatic COVID-19 in Japan.
Not available
S-EPMC7854735 | biostudies-literature
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