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MetabolomicsSerum protein N-glycosylation changes in multiple myeloma

BACKGROUND: Multiple myeloma is characterized by clonal proliferation of malignant plasma cells in the bone marrow that produce monoclonal immunoglobulins. N-glycosylation changes of these monoclonal immunoglobulins have been reported in multiple myeloma, but previous studies on...

2022-04-27 | MTBLS676 | MetaboLights
MetabolomicsFatty acid transport protein 4 is required for incorporation of saturated ultralong-chain fatty acids into epidermal ceramides and monoacylglycerols
Fatty acid transport protein 4 (FATP4) is an acyl-CoA synthetase that is required for normal permeability barrier in mammalian skin. FATP4 (SLC27A4) mutations cause ichthyosis prematurity syndrome, a nonlethal disorder. In contrast, Fatp4-/- mice die neonatally from a defective barrier. H...
2021-07-15 | MTBLS1138 | MetaboLights
MetabolomicsMetabolomics analysis was used to resolve metabolites affecting the protein oil content of soybean.
Soybean (Glycine max (L.)) originated in China more than 5000 years ago, and the country is currently the third largest producer of soybeans in the world (Hymowitz et al., 2015). Based on a wild soybean Chromosome Segment Substitution Line (CSSL) population were constructed by crossing with the cult...
2024-11-13 | MTBLS9424 | MetaboLights
ProteomicsInfluence of digestion protocol in Protein Quantitation
Quantitative determination of absolute and relative protein amounts is an essential requirement for most current bottom-up proteomics applications, but protein quantitation estimates are affected by several sources of variability such as sample preparation, mass spectrometric acquisition, and data a...
ORGANISM(S): Escherichia coli 
2014-07-30 | PXD001187 | Pride
Protein quantitation Digestion protocols Fasp 
MetabolomicsIdentification of BolA protein reveals a novel virulence factor in Klebsiella pneumoniae that contributes to liver abscess in mice

BolA has been characterized as an important transcriptional regulator, which is induced in the stationary phase of growth and is often associated with bacterial virulence. This study was initiated to elucidate the role of the BolA in the virulence of K. pneumoniae. Using a mous...

2022-09-13 | MTBLS2712 | MetaboLights
TranscriptomicsAntibody Array Figures
Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions. This study is described more fully in Haab, Dunham, and Brown, Genome Biology 2001 2(2): research0004.1-0004.13. Keywords: other
ORGANISM(S): Homo sapiens 
2002-06-27 | E-GEOD-50 | biostudies-arrayexpress
UnknownDeep proteomics of mouse skeletal muscle enables quantitation of protein isoforms, metabolic pathways, and transcription factors.
Not available
S-EPMC4390264 | biostudies-literature
ProteomicsAntigen array profiling for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions
Antigen Arrays from Figures 2, 4, and 6 of Haab, Dunham, and Brown, Genome Biology 2001 2(2): research0004.1-0004.13
ORGANISM(S): Homo sapiens 
2005-06-30 | E-SMDB-103 | biostudies-arrayexpress
ProteomicsQuantitation of plasma protein concentrations by mass spectrometry without the use of isotopic standards. C4PR_LIV
We applied a non targeted mass spectrometric assay (LCMSE), to quantify 55 abundant plasma proteins in specimens from 31 healthy volunteers. Quantitation was done by HI3 peptide measurement using a single internal standard to estimate protein concentrations. Results for 7 apolipoproteins were compar...
ORGANISM(S): Homo sapiens (Human) 
2015-10-20 | PXD000347 | Pride
Lcmse Quantitation Mass spectrometry Plasma proteins Proteomics Immunoassay 
ProteomicsAntibody array profiling for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions
Antibody Arrays from Figure 1 of Haab, Dunham, and Brown, Genome Biology 2001 2(2): research0004.1-0004.13
ORGANISM(S): Homo sapiens 
2005-06-30 | E-SMDB-101 | biostudies-arrayexpress
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