Sort   by:  
 Page size 
ProteomicsBirA*-RAB18 proximity biotinylation in HeLa cells
Proximity labelling using transient expression of the same exogenous BirA*-RAB18 construct in wild-type HeLa cells and in otherwise isogenic RAB3GAP1-, RAB3GAP2- and TRAPPC9-null HeLa cell lines.
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD016336 | Pride
Human Bira Hela Bioid 
Genomics2’3’-cGAMP binds and activates Rab18 to promote cell migration
2’3’-cGAMP binds and activates Rab18 to promote cell migration
PRJNA865774 | ENA
ProteomicsRab18 BioID Nov 24 2015 McGill University
BioID datasets of wt, Q and S in the absence and presence of oleate. Tetracyclin-induced Rab18-BirA* hybrid proteins stably expressed in HEK293 cells. Included also, NBirA* plus minus oleate induced and expressed as controls.
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD016631 | Pride
Rab18 bioid 
ProteomicsHDX-MS Analysis of the Rab3GAP1/Rab3GAP2
An HDX-MS analysis of the Rab3GAP1 and Rab3GAP2 subunit interface, and the binding interface between Rab18 and the full Rab3GAP1/2 complex.
ORGANISM(S): Homo sapiens (Human) 
2025-03-10 | PXD033072 | Pride
Hdx-ms Rab18 Rab3gap2 Rab3gap1 
ProteomicsRAB18 impacts autophagy via lipid droplet-derived lipid transfer and is rescued by ATG9A
Autophagy is a lysosomal degradation pathway that mediates protein and organelle turnover and maintains cellular homeostasis. Autophagosomes transport cargo to lysosomes and their formation is dependent on an appropriate lipid supply. Here, we show that the knockout of the RAB GTPase RAB18 interfere...
ORGANISM(S): Homo sapiens (Human) 
2020-01-29 | PXD013719 | Pride
Human Atg2b Rab18 Atg9a Lc-ms/ms 
UnknownRab18 and a Rab18 GEF complex are required for normal ER structure.
Not available
S-EPMC4050724 | biostudies-literature
Transcriptomics2’3’-cGAMP binds and activates Rab18 to promote cell migration
Cyclic dinucleotides serve as bacterial secondary messengers regulating sporulation, motility, biofilm formation and virulence. A nonsymmetric c-di-GAMP is firstly identified in bacteria to promote colonization, while mammalian 2’3’-cGAMP is synthesized by cGAS through binding and activating STING t...
ORGANISM(S): Homo sapiens 
2024-09-11 | GSE210490 | GEO
ProteomicsLFQP of lysates from wild-type, RAB18-, TBC1D20-, RAB3GAP1- and RAB3GAP2-null RPE1 cells
These data are from two wild-type RPE1 clones (WT11, WT20), a RAB18-null clone, a TBC1D20-null clone, a RAB3GAP1-null clone and a RAB3GAP2-null clone, each analysed in triplicate.
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD016326 | Pride
Human Rpe1 Rab18 Rab3gap1 Tbc1d20 Lfqp Rab3gap2 
ProteomicsRab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells
Rab GTPases recruit peripheral membrane proteins and can define organelle identity. Rab18 localizes to the ER but also to the surfaces of lipid droplets (LDs), where it has been implicated in effector protein recruitment and in defining LD identity. Here, we studied Rab18 localization and function i...
ORGANISM(S): Homo sapiens (Human) 
2018-06-06 | PXD009683 | Pride
Triacylglycerol Lipid droplet Endoplasmic reticulum Rab18 Neutral lipid storage Rabgtpase 
UnknownWarburg Micro syndrome is caused by RAB18 deficiency or dysregulation.
Not available
S-EPMC4632505 | biostudies-literature
Sort   by:  
 Page size