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TranscriptomicsDEPS-1 promotes P granule assembly and RNA interference in C. elegans germ cells
P granules are germ-cell-specific cytoplasmic structures containing RNA and protein and required for proper germ cell development in C. elegans. A new P-granule-associated protein, DEPS-1, whose loss disrupts P granule structure and function was analysed in this study. Genome wide analysis of gene...
ORGANISM(S): Caenorhabditis elegans 
2010-05-26 | E-GEOD-9993 | biostudies-arrayexpress
ProteomicsA simplified sample preparation for hair and skin proteins towards the application of archaeological fur and leather
Traditional protocols for proteomics analysis usually start by extracting or solubilizing the proteins from their substrates. This step can be challenging for archaeological proteins, when they are heavily contaminated or decayed. The remains of animal fur/leather objects from the singer’s burial of...
ORGANISM(S): Bos taurus (Bovine) Ovis aries 
2023-01-17 | PXD036745 | Pride
Collagen Archaeological burial Keratin Proteomics 
TranscriptomicsTranscriptome analysis Rhinolophus ferrumequinum (Rfe) cells upon poly-I:C transfection
Transcriptome analysis Rhinolophus ferrumequinum (Rfe) cells upon poly-I:C transfection. Rfe cell expressing human ACE2 and TMPRSS2 (Rfe-AT) and a SARS-Cov-2 / BANAL-236 successible clonal Rfe-AT cell line (Rfe-ATC) were transfected with poly-I:C or PBS and transcriptome was analysed using RNA seque...
ORGANISM(S): Rhinolophus ferrumequinum 
2026-04-10 | E-MTAB-16878 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of two human colon cancer cell lines treated with n-3 PUFA docosahexaenoic acid for 3 different time points
Several studies indicate that omega (n)-3 fatty acids may have a potential in the prevention and treatment of cancer. In this study the colon cancer cell lines SW480 and SW620 were treated with the n-3 PUFA DHA (Docosahexaenoic acid) for 3 different time points (12, 24 and 48h). The experiments were...
ORGANISM(S): Homo sapiens 
2008-04-01 | E-MEXP-1014 | biostudies-arrayexpress
ProteomicsUncovering deeply conserved motif combinations in rapidly evolving noncoding sequences
Here we focus on identifying conserved elements that are required for Chaserr function, a lncRNA that we recently characterized as being essential for mouse viability (https://doi.org/10.1038/s41467-019-13075-8). Chaserr is highly conserved in different species, and is located in close proximity (<2...
ORGANISM(S): Mus musculus (Mouse) 
2021-01-18 | PXD023093 | Pride
Conserved elements Chaserr Lncloom Lncrnas Dhx36 
ProteomicsIdentification of interactors of Arabidopsis VIN3 and VRN5 proteins in vernalized seedlings
The Arabidopsis VEL proteins VIN3 and VRN5 are accessory proteins of the Polycomb Repressive Complex 2 (PRC2). Their function is most well-understood in the epigenetic PRC2-mediated silencing of the floral repressor gene Flowering Locus C (FLC) during prolonged cold (vernalization). To identify prot...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-08-28 | PXD048844 | Pride
Prc2 Gene silencing Vernalization Epigenetics Polycomb Vel domain 
TranscriptomicsAtra effect on ERBB2 and RARA-coamplified SKBR-3 cells.
RNA was extracted with Rneasy Micro Kit (Qiagen, France) from SKBR3 cells treated with 1 uM ATRA. The quantity and purity of the extracted RNA was evaluated using a NanoDropTM spectrophotometer and its integrity measured using an Agilent BioanalyzerTM. For microarray hybridizations, 500 ng of total ...
ORGANISM(S): Homo sapiens 
2012-03-02 | E-MTAB-1013 | biostudies-arrayexpress
TranscriptomicsTranscriptional changes associated with miR-6762-5p expression in HCT116 cells
Decipher the direct and indirect targets of human miR-6762-5p by doxycyclin-inducible expression in HCT116 cells
ORGANISM(S): Homo sapiens 
2024-12-01 | E-MTAB-14122 | biostudies-arrayexpress
MetabolomicsMetabolomic analysis of the mechanism of action of yerba mate extract on Salmonella Typhimurium
Background: Salmonella Typhimurium is a gram-negative enteropathogen that infects millions worldwide; the rapid emergence of antibiotic resistant strains has heightened the urgency of developing effective treatment for this pathogen. Previous studies have demonstrated that the aqueous extract of yer...
2017-02-16 | MTBLS359 | MetaboLights
ProteomicsVRN1-associated proteins in Arabidopsis thaliana
The epigenetic silencing of the Arabidopsis floral repressor gene FLOWERING LOCUS C (FLC) is induced by a prolonged period of cold and promotes the developmental transition to flowering post-cold. FLC silencing requires the function of VRN1, a non-sequence-specific DNA binding protein. Here, we used...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-05-07 | PXD054597 | Pride
Arabidopsis Chromatin Epigenetic silencing Flowering 
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