Retinal vascular hyperpermeability

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Experimental Pharmacology Mannheim, European Center of Angioscience, Medical Faculty Mannheim, University Heidelberg, Mannheim, Germany (1)
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Mouse retinal tissue study in VEGF-induced hyperpermeability.

The goal of the project is to identify novel therapeutic targets for retinal vascular hyperpermeability. Three condition (Control, VEGF, and Anti-VEGF) sample of mouse retinal tissues were extensively characterized by global proteome profiling.

ORGANISM(S): Mus musculus (Mouse)

2016-03-22 | PXD003656 | Pride

Quantitative Proteomics Reveals β2 Integrin-mediated Cytoskeletal Rearrangement in Vascular Endothelial Growth Factor (VEGF)-induced Retinal Vascular Hyperpermeability.

Not available

S-EPMC4858948 | biostudies-literature

Aflibercept Suppression of angiopoietin-2 in a Rabbit Retinal Vascular Hyperpermeability Model.

Not available

S-EPMC10198290 | biostudies-literature

Diabetic vascular hyperpermeability: optical coherence tomography angiography and functional loss assessments of relationships among retinal vasculature changes.

Not available

S-EPMC7892857 | biostudies-literature

Interfering VE-cadherin Y685 Phosphorylation inhibits development of experimental diabetic and prediabetic retinopathy

Diabetic retinopathy involves early retinal vascular barrier breakdown and pericyte loss, yet the initiating molecular events remain poorly defined. Vascular endothelial cadherin (VE-cadherin), a key regulator of endothelial integrity, is notably reduced in diabetic and prediabetic nucleoside diphos...

ORGANISM(S): Mus musculus (Mouse)

2026-03-07 | PXD072047 | Pride

Y685 Pericyte Ve-cadherin Ndpkb Endothelial cell Metabolic Diabetic retinopathy

Evaluation of Molecular Properties versus In Vivo Performance of Aflibercept, Brolucizumab, and Ranibizumab in a Retinal Vascular Hyperpermeability Model.

Not available

S-EPMC9617509 | biostudies-literature

Apigenin and Ethaverine Hydrochloride Enhance Retinal Vascular Barrier In Vitro and In Vivo.

Not available

S-EPMC7409011 | biostudies-literature

Piezo2 protein: A novel regulator of tumor angiogenesis and hyperpermeability.

Not available

S-EPMC5190124 | biostudies-literature