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ProteomicsIntricate coupling between the transactivation and basic-leucine zipper domains governs the CK2-dependent phosphorylation of ATF4
Most transcription factors possess at least one long intrinsically disordered transactivation domain that binds to a variety of co-activators and co-repressors and plays a key role in modulating the transcriptional activity. Despite the crucial importance of these mechanisms, the structural and func...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD029704 | Pride
Atf4 Intrinsically disordered domain Phosphorylation Lc-msms 
UnknownImpact of hydrostatic pressure on an intrinsically disordered protein: a high-pressure NMR study of α-synuclein.
Not available
S-EPMC3874805 | biostudies-literature
UnknownProfiling the heterogeneity of colorectal cancer consensus molecular subtypes using spatial transcriptomics.
Not available
S-EPMC10781769 | biostudies-literature
TranscriptomicsTargeted RT-PCR assays spanning unannotated splice junctions sequenced by Roche 454.
The ENCODE projects seeks to identify and characterize functional elements in the human genome. Throughout the scale-up phase of ENCODE, the transcriptome group has generate Long RNA-Seq, Small RNA-Seq, Cap-Analysis of Gene Expression (CAGE), and RNA-PET short read data on the Illumina platform for...
ORGANISM(S): Homo sapiens 
2012-06-26 | E-GEOD-38886 | biostudies-arrayexpress
ProteomicsSplit-BioID - Split-BioID: a conditional proteomics approach for high resolution proteomics
Split-BioID: a conditional proteomics approach for high resolution proteomics
ORGANISM(S): Homo sapiens (Human) 
2017-06-01 | PXD005005 | Pride
Ltq orbitrap Hela cells 
ProteomicsSILAC & LC-MSMS in total cell extracts or in the secretome of POU5F1B- vs. GFP-overexpressing SW480 cells
The treatment of colorectal cancer (CRC) is an unmet medical need in absence of early diagnosis. Here, upon characterizing cancer-specific transposable element-driven transpochimeric gene transcripts (TcGTs) produced by this tumor, we found that expression of the hominid-restricted retrogene POU5F1B...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD028035 | Pride
Human Lc-msms Pou5f1b Silac Overexpression Sw480 Colorectal cancer 
ProteomicsSILAC & LC-MSMS in total cell extracts or in the secretome of sh-scramble vs. shRNA3 & shRNA5 LS1034 cells
The treatment of colorectal cancer (CRC) is an unmet medical need in absence of early diagnosis. Here, upon characterizing cancer-specific transposable element-driven transpochimeric gene transcripts (TcGTs) produced by this tumor, we found that expression of the hominid-restricted retrogene POU5F1B...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD028036 | Pride
Human Knock-down Lc-msms Pou5f1b Ls1034 Silac Colorectal cancer 
UnknownHuman Respiratory Syncytial Virus-Induced Immune Signature of Infection Revealed by Transcriptome Analysis of Clinical Pediatric Nasopharyngeal Swab Samples.
Not available
S-EPMC8006426 | biostudies-literature
UnknownRepurposing of Drugs as Novel Influenza Inhibitors From Clinical Gene Expression Infection Signatures.
Not available
S-EPMC6361841 | biostudies-literature
UnknownHealth care management adequacy among French persons with severe profound intellectual and multiple disabilities: a longitudinal study.
Not available
S-EPMC10795329 | biostudies-literature
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