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TranscriptomicsEvolutionary dynamics of gene and isoform regulation in mammalian tissues
Most mammalian genes produce multiple distinct mRNAs through alternative splicing, but the extent of splicing conservation is not clear.  To assess tissue-specific transcriptome variation across mammals, we sequenced cDNA from 9 tissues from 4 mammals and one bird in biological triplicate, at unprec...
ORGANISM(S): Mus musculus 
2012-12-21 | E-GEOD-41637 | biostudies-arrayexpress
TranscriptomicsStrand-specific RNA-seq of nine mouse tissues
This experiment is contains mouse organism part samples and strand-specific RNA-seq data from experiment E-GEOD-41637 (https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-41637/), which aimed at assessing tissue-specific transcriptome variation across mammals, with chicken used as an outgroup in e...
ORGANISM(S): Mus musculus 
2012-12-21 | E-MTAB-2801 | biostudies-arrayexpress
TranscriptomicsStrand-specific RNA-seq of nine rat tissues
This experiment is contains rat organism part samples and strand-specific RNA-seq data from experiment E-GEOD-41637 (https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-41637/), which aimed at assessing tissue-specific transcriptome variation across mammals, with chicken used as an outgroup in evo...
ORGANISM(S): Rattus norvegicus 
2012-12-21 | E-MTAB-2800 | biostudies-arrayexpress
TranscriptomicsStrand-specific RNA-seq of nine cow tissues
This experiment is contains cow organism part samples and strand-specific RNA-seq data from experiment E-GEOD-41637 (https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-41637/), which aimed at assessing tissue-specific transcriptome variation across mammals, with chicken used as an outgroup in evo...
ORGANISM(S): Bos taurus 
2012-12-21 | E-MTAB-2798 | biostudies-arrayexpress
TranscriptomicsStrand-specific RNA-seq of nine rhesus macaque tissues
This experiment is contains rhesus macaque organism part samples and strand-specific RNA-seq data from experiment E-GEOD-41637 (https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-41637/), which aimed at assessing tissue-specific transcriptome variation across mammals, with chicken used as an outg...
ORGANISM(S): Macaca mulatta 
2012-12-21 | E-MTAB-2799 | biostudies-arrayexpress
TranscriptomicsStrand-specific RNA-seq of nine chicken tissues
This experiment is contains chicken organism part samples and strand-specific RNA-seq data from experiment E-GEOD-41637 (https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-41637/), which aimed at assessing tissue-specific transcriptome variation across mammals, with chicken used as an outgroup in...
ORGANISM(S): Gallus gallus 
2012-12-21 | E-MTAB-2797 | biostudies-arrayexpress
ProteomicsER/PR RIME Experiments in MCF7 and T47D cell lines
Immuno-precipitation followed by MS was performed using the RIME protocol in this study. Estrogen Receptor (ER) and Progestorone Receptor (PR) were targetted using antibodies. The experiments were performed in a quantitative manner using SILAC labelling. Cells grown in complete serum (estrogenic) co...
ORGANISM(S): Homo sapiens (Human) 
2015-05-26 | PXD002104 | Pride
Pr Rime Estrogen receptor Progesterone receptor Er 
TranscriptomicsTranscription profiling of Zebrafish embryos investigating the effect of miR-430 microRNA on deadenylation and clearance of maternal mRNAs
MicroRNAs comprise 1-3% of all vertebrate genes, but their in vivo functions and mechanisms of action remain largely unknown. Zebrafish miR-430 is expressed at the onset of zygotic transcription and regulates morphogenesis during early development. Using a microarray approach and in vivo target vali...
ORGANISM(S): Danio rerio 
2007-10-05 | E-GEOD-4201 | biostudies-arrayexpress
ProteomicsARID1A RIME in human cell lines and tissue xenografts.
Examination of chromatin-bound proteins associated with ARID1A, BRG1 and ERa in MCF7 cells and ERa in ER+ patient-derived xenografts using RIME protocol and mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2019-10-31 | PXD011810 | Pride
Human Arid1a Rime Qplex 
ProteomicsHNF4G and FOXA1 are context-specific drivers of pancreatic cancer progression
Despite recent advances in the treatment of pancreatic adenocarcinoma (PDAC), clinical outcome remains poor. Previous evidence linked the pioneer transcription factor FOXA1 as a mediator of new regulatory elements that drive tumour progression in models of late-stage disease. Given the critical role...
ORGANISM(S): Homo sapiens (Human) 
2025-08-13 | PXD045980 | Pride
Foxa1 Pancreatic adenocarcinoma Hnf4g Rime 
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