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ProteomicsIn-depth mass spectrometry-based proteomics of formalin-fixed, paraffin embedded tissues with a spatial resolution of 50–200 µm
Formalin-fixed, paraffin-embedded (FFPE) tissues are banked in large repositories as a cost-effective means of preserving invaluable specimens for subsequent study, including for clinical proteomics in translational medicine. With the rapid growth of spatial proteomics, FFPE tissue samples can serve...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-02 | PXD029729 | Pride
Fresh frozen Spatial Ddm Ffpe Lcm 
ProteomicsFully automated sample processing and analysis workflow for low-input proteome profiling
Recent advances in sample preparation and analysis have enabled direct profiling of protein expression in single mammalian cells and other trace samples for characterization of cellular heterogeneity and high-resolution mapping of tissues. Several techniques used to prepare and analyze low-input sam...
ORGANISM(S): Homo sapiens (Human) 
2020-12-21 | PXD021882 | Pride
Low-input sample preparation Low-input proteomics 
UnknownLinking Skin and Joint Inflammation in Psoriatic Arthritis through Shared CD8+ T Cell Clones.
Not available
S-EPMC12854012 | biostudies-literature
ProteomicsFAIMS single cellUltrasensitive single-cell proteomics workflow identifies >1000 protein groups per mammalian cell
We report on the combination of nanodroplet sample preparation, ultra-low-flow nanoLC, high-field asymmetric ion mobility spectrometry (FAIMS), and the latest-generation Orbitrap Eclipse Tribrid mass spectrometer for greatly improved single-cell proteome coverage.
ORGANISM(S): Homo sapiens (Human) 
2020-12-21 | PXD022791 | Pride
Single-cell proteomics faims 
UnknownPsoriatic and rheumatoid arthritis joints differ in the composition of CD8+ tissue-resident memory T cell subsets.
Not available
S-EPMC10790246 | biostudies-literature
UnknownEvaluation of the Revised Versus Original Ryan White Part A HIV Care Coordination Program in a Cluster-Randomized, Stepped-Wedge Trial.
Not available
S-EPMC9936966 | biostudies-literature
ProteomicsBioinformatics Analysis of Top-Down Mass Spectrometry Data with ProSight Lite
Datafiles for Bioinformatics Analysis of Top-Down Mass Spectrometry Data with ProSight Lite
ORGANISM(S): Equus Caballus (ncbitaxon:9796) Bos Taurus (ncbitaxon:9913) 
2021-04-13 | MSV000087182 | MassIVE
UnknownHow do community-based eye care practitioners approach depression in patients with low vision? A mixed methods study.
Not available
S-EPMC6937690 | biostudies-literature
UnknownBarriers to integrating routine depression screening into community low vision rehabilitation services: a mixed methods study.
Not available
S-EPMC7448511 | biostudies-literature
ProteomicsCharacterization of RAS and SLC3A2 signaling in multiple myeloma
Oncogenic mutations within the RAS pathway are common in multiple myeloma (MM), an incurable malignancy of plasma cells. However, the mechanisms of pathogenic RAS signaling in this disease remain enigmatic and difficult to inhibit therapeutically. We employed an unbiased proteogenomic approach to ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD031662 | Pride
Phosphoproteomes Nras Kras Slc3a2 Bioid2 Multiple myeloma 
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