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UnknownCardiac manifestations in adult patients with inherited metabolic disease: A single-center experience.
Not available
S-EPMC12018057 | biostudies-literature
UnknownDiagnostic Accuracy of SARS-CoV-2 Rapid Antigen Detection Testing in Symptomatic and Asymptomatic Children in the Clinical Setting.
Not available
S-EPMC8373030 | biostudies-literature
UnknownNeutrophil HIF-1α stabilization is augmented by mitochondrial ROS produced via the glycerol 3-phosphate shuttle.
Not available
S-EPMC8832465 | biostudies-literature
ProteomicsA type I IFN, prothrombotic hyperinflammatory neutrophil signature is distinct for COVID-19 ARDS
Acute respiratory distress syndrome (ARDS) is a severe critical condition with a high mortality that is currently in focus given that it is associated with mortality caused by coronavirus induced disease 2019 (COVID-19). Neutrophils play a key role in the lung injury characteristic of non-COVID-19 A...
ORGANISM(S): Homo sapiens (Human) 
2021-02-03 | PXD023834 | Pride
Ards Type i ifn Sars-cov-2 Dexamethasone Neutrophil Covid-19 
ProteomicsHypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation
Hypoxemia is a defining feature of acute respiratory distress syndrome (ARDS), an often-fatal complication of pulmonary or systemic inflammation, yet the resulting tissue hypoxia, and its impact on immune responses, is often neglected. Here we showed that ARDS patients were hypoxaemic and monocytope...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2022-08-12 | PXD033151 | Pride
Ards Dia Classical monocytes Hypoxia 
UnknownHypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism.
Not available
S-EPMC8121528 | biostudies-literature
ProteomicsHypoxic regulation of the inflammatory lung neutrophil proteome
This project aimed to define the proteome of inflammatory lung neutrophils and determine how his is regulated by exposure to in vivo hypoxia. An acute lung injury was induced using nebulised LPS. Following LPS administration mice were housed in either normal room air or in a hypoxic chamber set at a...
ORGANISM(S): Mus musculus (Mouse) 
2021-04-08 | PXD013672 | Pride
Inflammation Hypoxia Lung Neutrophil 
UnknownProlyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses.
Not available
S-EPMC5669581 | biostudies-literature
UnknownSingle cell proteomic analysis defines discrete neutrophil functional states in human glioblastoma.
Not available
S-EPMC12816625 | biostudies-literature
ProteomicsSingle cell proteomics of human brain neutrophils from glioblastoma patients
FACS sorted single cell proteomes of glioblastoma derived neutrophils. Brain tissue was dissociated and individual neutrophils were FACS sorted into 384 well plates into master mix containing. The cells were later processed on the CellenOne and analysed on an Orbitrap Astral with FAIMS Pro. The data...
ORGANISM(S): Homo sapiens (Human) 
2025-11-18 | PXD061065 | Pride
Glioblastoma Scp Single cell Gbm Astral Brain Neutrophils Spectronaut 
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