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MetabolomicsDifferential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells
Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...
2022-11-15 | MTBLS2352 | MetaboLights
ProteomicsComparison of N- and O-glycosylation on Spike Glycoprotein 1 of SARS-CoV-1 and MERS-CoV
Coronaviruses (CoVs) are enveloped pathogens causing multiple respiratory disorders in humans with varying severity. Spike protein is one of the major proteins expressed on coronavirus surface, which mediates coronavirus entry into host cells. Spike proteins are extensively glycosylated and the glyc...
ORGANISM(S): Middle East respiratory syndrome-related coronavirus Severe acute respiratory syndrome coronavirus 
2025-04-07 | PXD062150 | Pride
Glycosylation Sars-cov-1 Mers-cov 
UnknownThe sequence at Spike S1/S2 site enables cleavage by furin and phospho-regulation in SARS-CoV2 but not in SARS-CoV1 or MERS-CoV.
Not available
S-EPMC7547067 | biostudies-literature
ProteomicsCortisol binding sites on SARS-CoV-2 S1 identified by limited proteolysis-coupled mass spectrometry
We used a limited proteolysis-coupled mass spectrometry approach to pinpoint binding sites of cortisol on SARS-CoV-2 S1. Binding target identification is based on the principle that small-ligand binding alters (increases or decreases) the protease accessibility of the target protein37,38. The bindin...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 
2022-06-10 | PXD032937 | Pride
Limited proteolysis Lc-ms Cortisol Covid-19 Sars-cov2 spike s1 
UnknownNovel T cell interferon gamma release assay (IGRA) using spike recombinant protein for COVID19 vaccine response and Nucleocapsid for SARS-Cov2 response.
Not available
S-EPMC8920083 | biostudies-literature
UnknownAnalyses of spike protein from first deposited sequences of SARS-CoV2 from West Bengal, India.
Not available
S-EPMC7309413 | biostudies-literature
UnknownBioinformatics prediction of B and T cell epitopes within the spike and nucleocapsid proteins of SARS-CoV2.
Not available
S-EPMC7737509 | biostudies-literature
ProteomicsSARS-CoV2 Immunocomplex by LC-MS/MS on vaccinated cohort
We describe the development of a highly specific, mulitplexed targeted proteomic LC-MS/MS assay for accurate quantitation of immunoprotective-proteins (including several classes of antibodies and complement) to SARS CoV2 S1 spike protein. We demonstrate how antibodies/complement levels can be monit...
ORGANISM(S): Homo Sapiens 
2022-07-14 | PXD028450 | panorama
GenomicsThe identification of a SARs-CoV2 S1 protein derived peptide with super-antigen-like stimulatory properties on T-cells
The identification of a SARs-CoV2 S1 protein derived peptide with super-antigen-like stimulatory properties on T-cells
PRJNA1182358 | ENA
UnknownThe SARS-CoV-2 spike S1 protein induces global proteomic changes in ATII-like rat L2 cells that are attenuated by hyaluronan.
Not available
S-EPMC10042596 | biostudies-literature
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