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BACKGROUND: Ischemia/reperfusion injury (IRI) is the leading cause of acute kidney injury (AKI). The current standard of care focuses on supporting kidney function, stating the need for more efficient and targeted therapies to enhance repair. Mesenchymal Stromal Cells (MSCs) and ...

2023-10-16 | MTBLS6279 | MetaboLights
Proteome and secretome quantitative LC-MS/MS (iTRAQ) of human THP-1 derived macrophages.
ORGANISM(S): Homo sapiens (Human) 
2020-10-15 | PXD017787 | Pride
To investigate BMP9/ALK1 signaling in human highly proliferative cells (hHiPC), we selected one primary population of hHiPC from 3 individuals and studied the secretome responses to BMP9 treatment. Proteins were collected in hHiPC treated conditioned media (CM) for mass spectrometry analysis. Proteo...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055302 | Pride
The excretory-secretory (ES) proteins are the molecules that actively or passively released by parasite at the parasite-host interface to maintain a physiological and immunological relationship with the host. In the present study, we characterised the excretory-secretory products from the short-term...
ORGANISM(S): Haemonchus contortus (Barber pole worm) 
2019-06-18 | PXD012503 | Pride
Osteocytes are secretory bone cells that can play an important role in regenerative rehabilitation through their secretome. Making use of RNA-seq and bioinformatics we examined the transcriptome of mouse and human osteocytic bone cells cultured under cyclic tension delivered by a computer-controlled...
ORGANISM(S): Mus musculus 
Macrophomina phaseolina is a global devastating necrotrophic fungal pathogen. It causes charcoal rot disease in more than 500 host plants. It is essential to understand the host microbe interaction and the diseases pathogenesis which can ensure global agricultural crop production and security. An ar...
ORGANISM(S): Macrophomina phaseolina MS6 
2022-05-20 | PXD032749 | Pride
To investigate the effect of glioblastoma secretome in activating tau pathology, Glioblastoma cell line secretome were prefractionated with gel filtration chromatography. Secretome analyzed by LC-MS/MS and identified targets using PSM count quantitation.
ORGANISM(S): Homo sapiens (Human) 
2018-07-16 | PXD007969 | Pride
Invasive pannus, mainly composed of fibroblast-like synoviocytes (FLSs), is a hallmark of rheumatoid arthritis (RA) pathology. Secreted proteins from RA-FLS play key roles in RA invasive pannus. However, RA-FLS-derived secretome associated with invasive pannus has not been systematically investigate...
ORGANISM(S): Homo sapiens (Human) 
2023-06-30 | PXD041077 | Pride
Microglia, astrocytes, and neurons, which have important functions in the central nervous system, communicate mutually to generate a signal through secreted proteins or small molecules, but many of which have not been identified. Because establishing a reference for the secreted proteins from CNS ce...
ORGANISM(S): Mus musculus (Mouse) 
2015-08-04 | PXD001597 | Pride
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