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Yeast sensor checkpoint kinase Mec1 is phosphorylated at Ser1991 upon HU replication stress. The phospho-accepter mutant (mec1-S1991A) confers HU sensitivity and synthetic sickness with the mutants that aggravate replication and transcription collision. To understand how the entire chromatin proteom...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-09-28 | PXD027337 | Pride
Large-scale interactome screen for 89 transcription factors (TFs) in fission yeast. TFs are tagged at the endogenous locus with a 3xFLAG affinity epitope. Cells cultured under optimal conditions (30°C, rich medium) were subjected to IP-MS at 150 mM an 500 mM NaCl.
ORGANISM(S): Schizosaccharomyces pombe 927 
2024-08-30 | PXD054070 | Pride
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