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MetabolomicsEvaluation of significant features discovered from different data acquisition modes in mass spectrometry-based untargeted metabolomics

Despite the growing popularity of liquid chromatography-mass spectrometry (LC-MS)-based metabolomics, no study has yet to systematically compare the performance of different data acquisition modes in the discovery of significantly altered metabolic features, which is an important task of untarget...

2020-10-02 | MTBLS1842 | MetaboLights
UnknownThe WRKY Transcription Factor GmWRKY12 Confers Drought and Salt Tolerance in Soybean.
Not available
S-EPMC6320995 | biostudies-literature
MetabolomicsLow chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
Dysregulated extravillous trophoblast invasion and proliferation are known to increase the risk of recurrent spontaneous abortion (RSA); however, the underlying mechanism remains unclear. Herein, in our retrospective observational case-control study we show that villous samples from RSA patients, co...
2021-10-06 | MTBLS2148 | MetaboLights
MetabolomicsNatural polymorphism of ZmICE1 contributes to amino acid metabolism that impacts cold tolerance in maize

Cold stress negatively affects maize (Zea mays L.) growth, development and yield. Metabolic adjustments contribute to the adaptation of maize under cold stress. We show here that the transcription factor INDUCER OF CBF EXPRESSION 1 (ZmICE1) plays a prominent role in reprogramming amino a...

2022-10-31 | MTBLS4404 | MetaboLights
ProteomicsN-glycoproteomic analysis of rice germinating embryo
N-glycoproteomic analysis of rice germinating embryo at 24 hours after inhibition
ORGANISM(S): Oryza sativa (Rice) 
2017-03-29 | PXD004417 | Pride
Glycosylation Lc-msms Embryo Rice (oryza sativa l.) Germination Proteome 
ProteomicsA Novel QconCAT-Based Proteomics Method for Determining Allele-Specific Protein Expression (ASPE)
In the present study, we developed a novel targeted proteomics approach for quantification of allele-specific protein expression (ASPE) based on scheduled high resolution multiple reaction monitoring (sMRM-HR) with a heavy stable isotope-labeled quantitative concatamer (QconCAT) internal protein sta...
ORGANISM(S): Homo sapiens (Human) 
2018-08-28 | PXD008788 | Pride
Human Allele-specific protein expression Liver 
UnknownGlycolysis-related biomarker TCIRG1 participates in regulation of renal cell carcinoma progression and tumor immune microenvironment by affecting aerobic glycolysis and AKT/mTOR signaling pathway.
Not available
S-EPMC10468907 | biostudies-literature
ProteomicsComparison of Protein Expressions of Drug-Metabolizing Enzymes between Human Liver and the Hepatic Cell Lines HepG2, Hep3B and Huh7 using SWATH and MRM-HR Proteomics
Human hepatic cell lines have been widely used as an in vitro model for the study of drug metabolism and liver toxicity. However, the validity of this model is still a subject of debate because the expressions of various proteins including drug-metabolizing enzymes (DMEs) in the cell lines can diffe...
ORGANISM(S): Homo sapiens (Human) 
2018-04-18 | PXD008190 | Pride
Hep3b Swath Human liver Huh7 Mrm-hr Proteomics Drug-metabolizing enzymes Hepg2 Protein expression 
UnknownMicrovascular and cellular dysfunctions in Alzheimer's disease: an integrative analysis perspective.
Not available
S-EPMC11385648 | biostudies-literature
MetabolomicsPlant elicitor peptide signalling confers rice resistance to piercing-sucking insect herbivores and pathogens
Rice is a staple food crop worldwide, and its production is severely threatened by phloem-feeding insect herbivores, particularly the brown planthopper (BPH, Nilaparvata lugens), and destructive pathogens. Despite the identification of many BPH resistance genes, the molecular basis of rice resistanc...
2022-02-23 | MTBLS3518 | MetaboLights
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