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ProteomicsGlobal mapping of short-lived proteins in human cells
Rapid protein degradation enables cells to quickly modulate protein abundance in response to stimuli. Previous studies have generally sought to delineate basic features of proteome turnover. A focused map of short-lived proteins, however, remains a missing piece of the human proteome. To begin to ad...
ORGANISM(S): Homo sapiens (Human) 
2022-02-07 | PXD024513 | Pride
Tmtpro Short-lived proteins Real-time search Cycloheximide 
ProteomicsConfounding factors in targeted degradation of short-lived proteins
Targeted proTargeted protein degradation has recently emerged as a novel option in drug discovery. Natural protein half-life is expected to affect the efficacy of degrading agents, but it has not been systematically explored to what extent it influences target protein degradation. Using mathematical...
ORGANISM(S): Homo sapiens (Human) 
2024-10-01 | PXD047934 | Pride
Protac. short-lived proteins Cancer Craf 
UnknownProteome-wide mapping of short-lived proteins in human cells.
Not available
S-EPMC8892350 | biostudies-literature
UnknownSProtP: a web server to recognize those short-lived proteins based on sequence-derived features in human cells.
Not available
S-EPMC3218052 | biostudies-literature
UnknownDevelopment of a method for screening short-lived proteins using green fluorescent protein.
Not available
S-EPMC545601 | biostudies-literature
UnknownRole of Sec61p in the ER-associated degradation of short-lived transmembrane proteins.
Not available
S-EPMC2442213 | biostudies-literature
UnknownDeep Learning for Hyperpolarized NMR of Intrinsically Disordered Proteins without Resolution Loss: Access to Short-Lived Intermediates.
Not available
S-EPMC12548504 | biostudies-literature
UnknownM-Track: detecting short-lived protein-protein interactions in vivo.
Not available
S-EPMC3428623 | biostudies-literature
UnknownShort-Lived Cages Restrict Protein Diffusion in the Plasma Membrane.
Not available
S-EPMC5057110 | biostudies-literature
UnknownAn "OFF-ON-OFF" fluorescence protein-labeling probe for real-time visualization of the degradation of short-lived proteins in cellular systems.
Not available
S-EPMC8809410 | biostudies-literature
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