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Data from ProteomeXchange, PXD ID: PXD001870. Experiment: Plasma membrane fraction R2 raw, file: 150120_106.mzml. Published as part of Nat Cell Biol. 2015 Oct 5 . From the Abstract: {{i}} Integrin-containing focal adhesions transmit extracellular signals across the plasma membrane to modulate cell ...
ORGANISM(S): Mus_musculus_viruses, Mouse 
We studied Receptor Tyrosine Kinase signalling from recycling endosomes and how this affected downstream responses. We developed a new method to study signalling in the proximity of recycling endosomes by combining enrichment of biotinylated peptides followed by enrichment of phosphorylated peptides...
ORGANISM(S): Homo sapiens (Human) 
2022-11-08 | PXD028371 | Pride
Stimulator of interferon genes (STING) is essential for the type I interferon response against a variety of DNA pathogens. Upon emergence of cytosolic DNA, STING translocates from the endoplasmic reticulum (ER) to the Golgi where STING activates the downstream kinase TBK1, then to lysosome through r...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-24 | PXD039411 | Pride
Activity-dependent bulk endocytosis (ADBE) is the dominant mode of synaptic vesicle (SV) endocytosis during high frequency stimulation, suggesting it should play key roles in neurotransmission during periods of intense neuronal activity. However efforts in elucidating the physiological role of ADBE ...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-10-15 | PXD009745 | Pride
We studied Receptor Tyrosine Kinase signalling from recycling endosomes and how this affected downstream responses.
ORGANISM(S): Homo sapiens (Human) 
2022-11-08 | PXD028370 | Pride
We studied Receptor Tyrosine Kinase signalling from recycling endosomes and how this affected downstream responses.
ORGANISM(S): Homo sapiens (Human) 
2022-11-08 | PXD028330 | Pride
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