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ProteomicsMouse cornea,sclera,skin LC-MSMS
We generated a P4ha2 knock-out mouse line (C57BL/6) by using CRISPR-Cas9 system. By mass spectrum, reduced proline hydroxylation was observed in collagens isolated from skin, sclera and cornea of P4ha2-/- mice.
ORGANISM(S): Mus musculus (Mouse) 
2026-03-02 | PXD023006 | Pride
Skin lc-msms Mouse cornea Sclera 
ProteomicsAgeing Mouse Skin LC-MSMS, NaCl extraction
Ageing compromises the mechanical properties of skin, with increased fragility and coincident slowing of the healing process making aged skin susceptible to chronic wounding. The ageing process is driven by an aggregation of damage to cells and extracellular matrix, compounded by regulatory changes,...
ORGANISM(S): Mus musculus (Mouse) 
2019-03-11 | PXD012754 | Pride
Ageing Mouse skin 
ProteomicsMalassezia sympodialis host response studied with an ex-vivo human skin model
An ex-vivo human skin model was used to investigate the host skin response to M. sympodialis on oily (supplemented with oleic acid) and non-oily skin. Host-pathogen interactions were analysed by different molecular techniques including proteomics.
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD018404 | Pride
Lc-msms Infection model Malassezia sympodialis Human skin 
ProteomicsYoung, old, OVX mouse Skin LC-MSMS, 3M Urea extraction
Ageing compromises the mechanical properties of skin, with increased fragility and coincident slowing of the healing process making aged skin susceptible to chronic wounding. The ageing process is driven by an aggregation of damage to cells and extracellular matrix, compounded by regulatory changes,...
ORGANISM(S): Mus musculus (Mouse) 
2019-03-11 | PXD012753 | Pride
Ovx Mouse Skin Ageing 
ProteomicsProteomic analysis revealed gender-related differences in the skin mucus proteome of discus fish (Symphysodon haraldi) during the parental and non-parental care periods
The discus fish, Symphysodon spp., a South American cichlid, has a unique parental care behavior where fry bite on parental skin mucus after hatching. In this study, we used LC-MS/MS technique to compare the skin mucus proteome composition of male or female discus fish during parental and non-parent...
ORGANISM(S): Symphysodon Haraldi 
PXD054942 |
ProteomicsProteomics of Skin Proteins in Psoriasis
Herein we demonstrate the efficacy of an unbiased proteomics screening approach for studying protein expression changes in the KC-Tie2 psoriasis mouse model, identifying multiple protein expression changes in the mouse and validating these changes in human psoriasis. KC-Tie2 mouse skin samples (n=3...
ORGANISM(S): Mus musculus (Mouse) 
2014-10-30 | PXD001387 | Pride
Psoriasis Trangenic mouse Lc-msms 
ProteomicsRDEB Mouse Model - Losartan ameliorates dystrophic epidermolysis bullosa and uncovers new disease mechanisms
Expression proteomics of back skin of collagen VII (C7) hypomorphic and WT mice was performed to detect differences in the skin proteome dependent on the presence of collagen VII and the treatment with losartan.
ORGANISM(S): Mus musculus (Mouse) 
2015-10-02 | PXD002134 | Pride
Lc-msms Collagen vii Epidermolysis bullosa Hypomorphic mouse Skin Losartan 
ProteomicsSkin Exposure to UVB Light induces a Skin-Brain-Gonad Axis and Sexual Behavior
Ultraviolet (UV) light affects endocrinological and behavioral aspects of human sexuality via an unknown mechanism. Using a unique male-female comparative approach, we discovered that the sexual behavioral and hormonal features enhanced by UVB are mediated by the skin. In mice, UV exposure increases...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-17 | PXD025973 | Pride
Proteomics Uvb light Sexual behavior 
ProteomicsMouse skin pericytes LC-MSMS data
Proteomic analysis was conducted to investigate the potential downstream targets of MAT2A.
ORGANISM(S): Mus musculus (Mouse) 
2025-08-28 | PXD067803 | Pride
Lc-msms Mouse Pericytes 
ProteomicsTime course differential profiles of proteins expressed in Holotrichia serrata during tritrophic interaction among EPN and associated bacteria. LC-MSMS
Entomopathogenic nematodes, the beneficial soil-dwelling nematodes identified with noteworthy ecological services of insect pest management naturally, harbor and vector obligate bacterial symbionts which together cause rapid insect mortality. The tritrophism among the bacterium-nematode-insect host ...
ORGANISM(S): Holotrichia Serrata 
2025-01-10 | PXD048306 | JPOST Repository
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