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Co-housed young adult CEABAC10-transgenic mice (CEA) with C57BL/6NRj background and their wild type littermates (WT) were injected with 1 × 10*4 CFU C. albicans/g body weight via the lateral tail vein (Ca). Control mice received endotoxin-free buffered saline solution (PBS). Mice were sacrificed aft...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-25 | PXD061893 | Pride
Exposure of human monocytes to lipopolysaccharide (LPS) or other pathogen-associated molecular pattern (PAMPs) induces a temporary insensitivity to subsequent LPS challenges, a cellular state called endotoxin tolerance (ET). The tolerant state of monocytes is accompanied by cell surface and other gl...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD036036 | Pride
Comprehensive proteomic analysis of the protein expression landscape of bronchoalveolar lavage fluid during invasive pulmonary aspergillosis in murine and human samples. 38 murine BALF samples (10 Aspergillus fumigatus infected mice without immunosuppression and without invasive pulmonary aspergillo...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2020-10-14 | PXD016664 | Pride
CD14+ Monocytes from healthy volunteers were purified by MACS (negative selection) and FACSorting and either left untreated or stimulated for 24h and 48h with LPS. THP-1 cells were stimulated for 4h, 24h and 48h with LPS. Glycoproteins were captured with hydrazide chemistry and tryptic and PNGase F-...
ORGANISM(S): Homo sapiens (Human) 
2017-04-24 | PXD004034 | Pride
In-depth proteome exploration of complex body fluids is a challenging task that requires optimal sample preparation and analysis in order to reach novel and meaningful insights. Analysis of follicular fluids is similarly difficult as that of blood serum due to the ubiquitous presence of several high...
ORGANISM(S): Homo sapiens (Human) 
2018-12-04 | PXD009061 | Pride
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