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ProteomicsCoexistence of Pseudomonas aeruginosa with Candida albicans enhances biofilm thickness through increased extracellular matrix from both organisms, but is attenuated by N-acetyl-L-cysteine
Biofilms are a communal of one or several kinds of microorganisms that growing on of both non-living and biotic surfaces by the production of multi-layers high-abundance extracellular matrix (ECM) to survive in the harsh environments (1-4). Biofilms consist of 85% (by volume) of matrix materials and...
ORGANISM(S): Pseudomonas aeruginosa PAO1H2O Candida albicans 24C 
2021-09-09 | PXD020949 | Pride
Pseudomonas aeruginosa Biofilm Extracellular matrix 
ProteomicsOsteogenic differentiation regulation of canine periodontal ligament stem cells by hydrogel containing magnetic nanoparticles
Bone defect architecture has become an issue to resemble in scaffold properties, beside enhancing osteoinduction. Thus, a non-invasive injectable approach is proposed by using silk fibroin (SF)-based hydrogel containing magnetic nanohydroxyapatite (MHAp) and osteogenic growth peptide (OGP). This stu...
ORGANISM(S): Canis lupus lupus 
2026-05-25 | PXD063171 | Pride
Hydrogel Osteogenic Canine periodontal ligament stem cells 
ProteomicsProtein expression of Isolated B cells from splenocytes in collagen-induced arthritis (CIA) model between Wildtype (C57BL/6) and Stinggt/gt mice.
The pathogenesis of rheumatoid arthritis (RA) is complicated and involves both innate and adaptive immunity [5]. The innate immunity such as macrophages or fibroblast-like synoviocytes (FLS) in the synovium can generate inflammatory mediators, including TNF-α, IL-1, IL-6, IL-17, IFN-γ, and chemo kin...
ORGANISM(S): Mus musculus (Mouse) 
2020-06-26 | PXD018652 | Pride
Quantitative proteomics Sting Collagen-induced arthritis 
ProteomicsComprehensive proteomics identification of IFN-λ3-regulated anti-viral proteins in HBV-transfected cells
Hepatitis B virus (HBV) causes both acute and chronic liver inflammation. Approximately 600,000 CHB patients each year die of HBV-related diseases such as cirrhosis and liver cancer. Therefore, CHB remains a global health concern. Although there have been anti-HBV agents for treating CHB, they have ...
ORGANISM(S): Homo sapiens (Human) 
2018-08-17 | PXD007896 | Pride
Hepatitis b virus Ifn-λ3 Dimethyl labeling Lc-ms/ms 
ProteomicsMultiple Extracellular Vesicle Types in Peritoneal Dialysis Effluent are Prominent and Contain Known Biomarkers
Proteomics-based analysis of Peritoneal Dialysis Effluent is a relatively new approach to studying the changes associated with PD. Recent studies have shown altered proteomic profiles in various conditions of PD patients, including uremia, diabetes, peritonitis, abnormal peritoneal transport functi...
ORGANISM(S): Homo sapiens (Human) 
2018-08-14 | PXD006371 | Pride
Peritoneal dialysis Extracellular vesicles Proteomics 
ProteomicsProteomic profiling of ubiquitylated proteins in urinary exosomes
Exosomes, derived from multivesicular bodies (MVBs), contain proteins and genetic materials from their cell of origin and are secreted from various cells types, including kidney epithelial cells. In general, it is thought that protein cargo is ubiquitylated, but that ubiquitin is cleaved by specific...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-21 | MSV000080269 | MassIVE
ProteomicsDifferent osteogenic differentiation behavior of canine mesenchymal stem cells derived from bone marrow and dental pulp: the proteomics profile
Although various sources of cMSCs show similar characteristics, they are different in osteogenic potential due to their original cellular sources. Thus, this study was designed to globally explore and analyze the in vitro differentiation potential and behavior of canine bone-marrow derived mesenchym...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2021-09-08 | PXD015512 | Pride
Osteogenic differentiation Canine bone-marrow derived mesenchymal stem cells (cbm-mscs) Canine dental pulp stem cells (cdpscs) Systems biology 
ProteomicsDeep Characterization of the IFN-I/III-Stimulated Proteome in HBV-Transfected or Native HepG2 Cells
To expand knowledge of the effects of interferon at the proteomic level, we treated HepG2 cells with IFN-alpha and IFN-lambda for 24 hours. HepG2.2.15 cells, a model for HBV infection, were also examined versus controls. MTT assays showed that optimized IFN levels (100 ng/ml) did not induce apoptosi...
ORGANISM(S): Homo sapiens (Human) HBV genotype D 
2020-06-26 | PXD017251 | Pride
Quantitative proteomics Hepatitis b virus Interferon alpha Interferon lambda3 
ProteomicsMass Spectrometry-Driven Epitope Mapping: Application of Diethylpyrocarbonate Covalent Labeling for the Immunotherapeutic Target Programmed Cell Death Protein 1
Monoclonal antibodies (mAbs) have transformed cancer immunotherapy, with anti-PD1 mAbs playing a pivotal role. This study introduces diethylpyrocarbonate covalent labeling-mass spectrometry (DEPC CL-MS) as a rapid and sensitive technique for epitope mapping of PD1, a critical target in mAb developme...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-11-26 | MSV000096536 | MassIVE
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