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During acute oxidative phosphorylation (OXPHOS) dysfunction, the reverse activity of succinate dehydrogenase (Complex II) maintains the redox state of the Coenzyme Q pool by utilizing either fumarate or oxygen as terminal electron acceptors. The tendency for one over another has been suggested to be...
ORGANISM(S): Homo sapiens (Human) 
2025-06-06 | PXD064653 | Pride
During acute oxidative phosphorylation (OXPHOS) dysfunction, the reverse activity of succinate dehydrogenase (Complex II) maintains the redox state of the Coenzyme Q pool by utilizing either fumarate or oxygen as terminal electron acceptors. The tendency for one over another has been suggested to be...
ORGANISM(S): Homo sapiens (Human) 
2025-06-06 | PXD064649 | Pride
Membrane contact sites between organelles are critical for transfer of biomolecules. Lipid droplets store fatty acids and form contacts with mitochondria, which regulate fatty acid oxidation and adenosine triphosphate production. Protein compartmentalization at lipid droplet-mitochondria contact sit...
ORGANISM(S): Homo sapiens (Human) 
2025-04-28 | PXD060912 | Pride
Understand mitochondrial DNA polymerase mutated in context of organ/cell function. Resulting in mitochondrial proteome landscape shift, DNA mutation and instability. Impact cardiac phenotypes in the POLG mutant mouse. Label free/spectral library data
ORGANISM(S): Mus musculus (Mouse) 
2025-02-11 | PXD039029 | Pride
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