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TranscriptomicsTranscription profiling of Xenopus laevis gastrula ventral and dorsal halves at NF stages 10 and 11.5 injected with noggin and dkk-1 plasmid
Studies of the Xenopus organizer have laid the foundation for our understanding of the conserved signaling pathways that pattern vertebrate embryos during gastrulation. Here, we use this wealth of knowledge as leverage in the design and analysis of a genomic visualization of organizer-related gene ...
ORGANISM(S): Xenopus laevis 
2007-10-05 | E-GEOD-3368 | biostudies-arrayexpress
GenomicsBighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis
Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis
PRJNA416291 | ENA
UnknownMolecular mechanisms of cell-cell signaling by the Spemann-Mangold organizer.
Not available
S-EPMC2354921 | biostudies-literature
UnknownMink1 regulates spemann organizer cell fate in the xenopus gastrula via Hmga2.
Not available
S-EPMC10116378 | biostudies-literature
UnknownTranscriptional integration of Wnt and Nodal pathways in establishment of the Spemann organizer.
Not available
S-EPMC3572767 | biostudies-literature
UnknownThe tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer.
Not available
S-EPMC6996932 | biostudies-literature
UnknownSiamois and Twin are redundant and essential in formation of the Spemann organizer.
Not available
S-EPMC3065516 | biostudies-literature
ProteomicsMink1 Kinase Regulates Dorsal Mesodermal Cell Fate in the Xenopus Gastrula via HMGA2
Congenital Heart Disease (CHD) is the most common birth defect and leading cause of infant mortality, yet molecular mechanisms explaining CHD remain mostly unknown. Sequencing studies are identifying CHD candidate genes at a brisk rate including MINK1, a serine/threonine kinase. However, a plausible...
ORGANISM(S): Xenopus tropicalis 
2024-05-22 | PXD028827 | Pride
Left right patterning Beta catenin Xenopus Hmga2 Mink1 Wnt signaling Spemann organizer Congenital heart disease Gastrulation 
UnknownFrzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer.
Not available
S-EPMC3061830 | biostudies-literature
UnknownMitochondrial leak metabolism induces the Spemann-Mangold Organizer via Hif-1α in Xenopus.
Not available
S-EPMC10840693 | biostudies-literature
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