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TranscriptomicsSCL005: icSARS CoV Urbani or icSARS deltaORF6 infections of the 2B4 clonal derivative of Calu-3 cells - Time course
Purpose of experiment was to compare transcriptomics of 2B4 cells (clonal derivative of Calu-3 cells) infected with either icSARS CoV or the icSARS deltaORF6 mutant. Calu-3 cells were infected with either icSARS CoV or the icSARS deltaORF6 mutant at MOI of 5.0. Cells samples were collected at 0, 3,...
ORGANISM(S): Homo sapiens 
2011-11-01 | E-GEOD-33267 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis mutants (elo2, elo3, drl1-2 and ang4) vs the wild type Ler strain
Microarray transcript profiling and RNA interference are two new technologies crucial for large-scale gene function studies in multicellular eukaryotes. Both rely on sequence-specific hybridization between complementary nucleic acid strands, inciting us to create a collection of gene-specific sequen...
ORGANISM(S): Arabidopsis thaliana 
2004-05-07 | E-MEXP-30 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human cells expressing FoxM1-ER fusion protein
Experiment description To identify FoxM1-regulated genes, we carried out gene expression profile analysis after inducible activation of a FoxM1-ER fusion protein using high-density human cDNA microarrays. We constructed a stable line of U2OS cells expressing full-length HA-FoxM1 fused at its C-term...
ORGANISM(S): Homo sapiens 
2005-01-01 | E-MEXP-230 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Atlantic salmon infected with salmoin alphavirus
Salmon pancreas disease, caused by salmonid alphavirus (SAV), is an economically important disease affecting farmed Atlantic salmon (Salmo salar L.) in Europe, with outbreaks reported in Scotland, Norway, and Ireland. A microarray-based study was performed to evaluate the host transcriptomic respons...
ORGANISM(S): Salmo salar 
2011-06-01 | E-TABM-1060 | biostudies-arrayexpress
ProteomicsGlycosite mapping and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE
Mucin-domain glycoproteins are densely O-glycosylated and play key roles in a host of biological functions. In particular, the T-cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, 3, 4) decorate immune cells and act as key checkpoint inhibitors in cancer. However, their dense...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2023-09-27 | PXD039583 | Pride
O-glycoprotein Tim-1 Cancer Mucinase Tim-4 Tim-3 O-glycosylation Immune checkpoint T-cell immunoglobulin and mucin-domain containing Lc-ms/ms Molecular dynamics Mucinome Mucin O-glycoproteomics Mucin domain Checkpoint inhibitor O-glycoprotease 
TranscriptomicsmRNA-Seq of Lemna minor exposed to different concentrations of sucralose against untreated control groups
The experiment investigates how the artificial sweetener sucralose affects gene expression in the teleost fish Danio rerio in order to derive mechanistic information relevant for environmental risk assessment. The main test including transcriptomics, was conducted with 10 µg/L and 100 mg/L as test c...
ORGANISM(S): Lemna minor 
2026-04-30 | E-MTAB-16758 | biostudies-arrayexpress
TranscriptomicsmRNA-Seq of Lemna minor exposed to different concentrations of the pharmaceutical atorvastatin against untreated control groups
In this study, Lemna minor was used to investigate ecotoxic modes-of-action (MoA) at the gene expression level. For this purpose, mRNA sequencing was applied to plant RNA extracted from L. minor exposed to the pharmaceutical atorvastatin in a shortened version of the OECD guideline test No. 221 (OEC...
ORGANISM(S): Lemna minor 
2022-07-15 | E-MTAB-11459 | biostudies-arrayexpress
TranscriptomicsmRNA-Seq of Lemna minor exposed to different concentrations of the herbicide bentazon against untreated control groups
In this study, Lemna minor was used to investigate ecotoxic modes-of-action (MoA) at the gene expression level. For this purpose, mRNA sequencing was applied to plant RNA extracted from L. minor exposed to the herbicide bentazon in a shortened version of the OECD guideline test No. 221 (OECD TG 221)...
ORGANISM(S): Lemna minor 
2022-07-15 | E-MTAB-11460 | biostudies-arrayexpress
TranscriptomicsTelomeric DNA damage response activation mediates idiopathic pulmonary fibrosis caused by telomere dysfunction
Lungs from wild type and Terc KO mice, treated with DDR inhibitors
ORGANISM(S): Mus musculus 
2026-07-10 | E-MTAB-14908 | biostudies-arrayexpress
UnknownThe genomic landscape of hypodiploid acute lymphoblastic leukemia.
Not available
S-EPMC3919793 | biostudies-literature
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