Stress granules.

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Organisms

Homo sapiens (101)
Mus musculus (51)
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Arabidopsis thaliana (8)
Escherichia coli str. K-12 substr. MG1655 (3)
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feces metagenome (1)
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Technology Type

Mass Spectrometry (143)
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Instrument Platform

Orbitrap Fusion Lumos (8)
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Publication Date

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2005 (2)

CHEBI ID

CHEBI:81750 (1)
CHEBI:229940 (1)
CHEBI:174326 (1)
CHEBI:39745 (1)
CHEBI:32381 (1)
CHEBI:192883 (1)
CHEBI:136372 (1)
CHEBI:89232 (1)
CHEBI:229945 (1)
CHEBI:141366 (1)
CHEBI:170316 (1)
CHEBI:190161 (1)
CHEBI:137332 (1)
CHEBI:88434 (1)
CHEBI:169002 (1)
CHEBI:89184 (1)
CHEBI:170694 (1)
CHEBI:190173 (1)
CHEBI:89680 (1)
CHEBI:89506 (1)
CHEBI:190154 (1)
CHEBI:190169 (1)
CHEBI:170425 (1)
CHEBI:88859 (1)
CHEBI:89500 (1)
CHEBI:190153 (1)
CHEBI:171009 (1)
CHEBI:89977 (1)
CHEBI:190167 (1)
CHEBI:86182 (1)

Metabolite Name

Allantoin (3)
Sebacic acid (3)
Azelaic acid (3)
Uridine (3)
Pseudouridine (3)
Hippuric acid (3)
2-Ketohexanoic acid (2)
D-Glucuronic acid (2)
P-Toluenesulfonic acid (2)
N-Acetyl-L-methionine (2)
Phenobarbital (2)
2-Ketobutyric acid (2)
Isovalerylglycine (2)
2-Hydroxy-3-methylbutyric acid (2)
4-Nitrophenol (2)
Uracil (2)
Cinnamoylglycine (2)
Pyroglutamic acid (2)
Orotic acid (2)
Indoxyl sulfate (2)
2-Isopropylmalic acid (2)
4-Pyridoxic acid (2)
Nicotinic acid (2)
Kynurenic acid (2)
Phenyllactic acid (2)
Benzoic acid (2)
Indole-3-carboxylic acid (2)
Maleic acid (2)
Eicosapentaenoic acid (2)
Thromboxane B2 (2)

First Public Date

2024 (55)
2025 (43)
2026 (33)
2023 (22)
2022 (19)
2021 (16)
2016 (14)
2018 (9)
2017 (9)
2020 (8)
2019 (8)
2014 (7)
2015 (5)
2013 (3)

Modelling Approach

Mathematical model (1)
Ordinary differential equation model (1)

Study status

Completed (1)

Lab affiliation

Department of Biochemistry and Functional Proteomics, Institute of Biology II, Faculty of Biology and Signalling Research Centres BIOSS and CIBSS, University of Freiburg, 79104 Freiburg im Breisgau, Germany (5)
Department of Cell & Developmental Biology, University of California, San Diego, CA 92093, USA. (3)
Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada K1H 8M5 (3)
First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China (3)
Medizinisches Proteom-Center, Medical Faculty, Ruhr-University Bochum, Bochum, Germany (3)
Department of Experimental Neurodegeneration, University Medical Center Goettingen (2)
Goethe University Frankfurt, University Hospital, Clinic of Neurology, Experimental Neurology, Heinrich Hoffmann Str. 7, 60590 Frankfurt am Main, Germany (2)
Institute of Biochemistry II, Goethe University, Medical School, Frankfurt, Germany (2)
Key Laboratory for Experimental Teratology of the Ministry of Education, Advanced Medical Research Institute, Qilu Hospital, Cheeloo College of Medicine, Shandong University (2)
Proteomics Core Facility and Research Group Proteomics, CEITEC-MU, Masaryk University, Brno, Czech Republic (2)
School of Medicine, Sun Yat-sen University (2)
Shenzhen Key Laboratory of Plant Genetic Engineering and Molecular Design, Institute of Plant and Food Science, Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China (2)
State Key Laboratory for Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China (2)
University of Edinburgh (2)
1. Department of Experimental Neurodegeneration, University Medical Center Goettingen, Germany 2. 1Base Pharmaceuticals, Boston, MA 02129, USA (1)
1Centre for Bioscience, Manchester Metropolitan University, Manchester, UK (1)
Affiliation of Zhengting Chen, Jing Wang, Hebo Zhao, Yaping Yue, Biao Liu, Yu Zhao, Dao-Xiu Zhou: National Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University, 430070 Wuhan, China (1)
Beijing, You An Men Wai Xi Tou Tiao No.10, Capital Medical University, Beijing Laboratory of Oral Health (1)
Biochemistry and Molecular Biology, The Institute for Medical Research Israel-Canada (IMRIC). School of Medicine. The Hebrew University of Jerusalem, Israel. (1)
Biological and Environmental Science and Engineering Division King Abdullah University of Science and Technology (KAUST) (1)
Buchmann Institute of Molecular Life Sciences and Institute of Biophysical Chemistry, Goethe University, Frankfurt am Main, Germany (1)
CEA-Marcoule, ProGénoMIX platform, DRF-Li2D, 30207 Bagnols-sur-Cèze, France (1)
CECAD, Institute for Integrated Stress Response Signaling, Faculty of Medicine, University Hospital of Cologne (1)
CEITEC, Masaryk University Molecular medicine, RNA and immunity, CEITEC, Masaryk University (1)
Cambridge Institute for Medical Research, University of Cambridge; Cambridge, UK (1)
Cancer Research Center of Toulouse (CRCT) 2 Avenue Hubert Curien 31037 Toulouse (1)
Cell Signaling and Clinical Proteomics Group, Biocruces Bizkaia Health Research Institute, 48903 Barakaldo (Spain) (1)
Cell Signalling and Proteomics Group, Centre for Genomics and Computational Biology, Barts Cancer Institute, Queen Mary University of London, London, EC1M6BQ, UK (1)
Center for Natural Product Systems Biology, Korea Institute of Science and Technology (1)
Centre for Molecular Biology at the university Heidelberg (ZMBH), Im Neuenheimer Feld 282; 69120 Heidelberg, Germany (1)

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Classification

bacteria (4)
viruses (2)
fungi (1)
protozoa (1)

Study type

Transcription profiling by array (25)
RNA-seq of coding RNA (9)
Unknown experiment type (2)
ChIP-chip by array (2)
Cell line - High-throughput sequencing (1)
RNAi profiling by array (1)
Other (1)
Methylation profiling by array (1)
Interventional (1)

Release Date

2023 (151)
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2019 (87)
2015 (67)
2018 (64)
2016 (63)
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2014 (46)
2013 (43)
2011 (32)
2026 (23)
2012 (23)
2010 (23)
2008 (20)
2007 (14)
2009 (11)
2006 (9)
2005 (3)
2004 (2)
2002 (1)
2000 (1)

Location

Malaysia (1)

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PKA regulates stress granule maturation to allow timely recovery after prolonged starvation

Cells have evolved multiple strategies to survive environmental stress conditions. This includes the formation of membrane-less cytoplasmic ribonucleoprotein structures called stress granules that sequester and protect mRNAs encoding many housekeeping genes. Stress granules are not static biomolecul...

2026-06-16 | MTBLS13923 | MetaboLights

RNA localization to stress granules

PRJNA875210 | ENA

RIOK1 Phase Separation Shapes Stress Adaptation and Cell Fate in Hepatocellular Carcinoma

Cancer cells can always be unexpected rescued from desperate environment by mounting adaptive responses to resolve the arising cellular stress. The dynamic stress granules (SGs) assembly and metabolic reprogramming play crucial roles in maintaining cellular growth and homeostasis. However, the me...

2025-02-26 | MTBLS11963 | MetaboLights

ECT2 and AURKB Modulate Formation of Stress Granules Containing Transcripts from Diverse Cellular Pathways in Astrocytoma Cells

Stress granules are small RNA-protein granules that modify the translational landscape during cellular stress to promote survival. The RhoGTPase RhoA is implicated in the formation of RNA stress granules. Our data demonstrate that the cytokinetic proteins ECT2 and AurkB are localized to stress gran...

ORGANISM(S): Homo sapiens

2016-02-29 | E-GEOD-76814 | biostudies-arrayexpress

Proteome of lysate granules using G3BP and ASPL, and changes in the G3BP interactome caused by ASPL depletion

ORGANISM(S): Homo sapiens (Human)

2025-08-16 | PXD059889 | Pride

The stress granule transcriptome reveals principles of mRNA accumulation in stress granules.

PRJNA388080 | ENA

The Proteome and Transcriptome of Stress Granules and P-Bodies during Human T Lymphocytes Activation

Stress granules (SGs) and processing bodies (PBs) are membraneless cytoplasmic assemblies regulating mRNAs under environmental stress such as viral infections, neurological disorders, or cancer. Upon antigen stimulation, T lymphocytes mediate their immune functions under regulatory mechanisms involv...

ORGANISM(S): Homo sapiens (Human)

2023-03-10 | PXD031639 | Pride

Human t lymphocytes Ribonucleoprotein granules Proteome

Stress Granules FUS WT e FUS P525L

Stress Granules (SG) formation is a cellular protection mechanism, constituting a storage for untranslated mRNAs and RNA-binding proteins (RBPs); however, these condensates can turn into pathological aggregates, related to the onset of neurodegenerative diseases like Amyotrophic Lateral Sclerosis (A...

ORGANISM(S): Homo sapiens (Human)

2025-05-06 | PXD049234 | Pride

Stress granules Als Rna-binding proteins Neurodegeneration Aggregation

Fasnall induces atpically transient Stress Granules

Stress Granule formation has been linked to the resistance of some cancer cells to chemotherapeutic intervention. A number of studies have proposed that certain anti-tumor compounds promote cancer cell survival by inducing Stress Granules formation, leading to increased cellular fitness and apoptosi...

ORGANISM(S): Homo sapiens (Human)

2021-09-09 | PXD021229 | Pride

Stress granule Fasnall Pabpc1

Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and shape their functional biology

The human genome is replete with sequences derived from foreign elements including endogenous retrovirus-like proteins of unknown function. The human genome is replete with sequences derived from foreign elements including endogenous retrovirus-like proteins of unknown function. Here we show that UB...

ORGANISM(S): Homo sapiens (Human)

2025-06-04 | PXD061852 | Pride

Stress granules Retrotransposon-derived proteins Ubiquilins

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