Striatal - OmicsDI

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Organisms

Mus musculus (287)
Homo sapiens (64)
Rattus norvegicus (35)
Taeniopygia guttata (10)
Macaca mulatta (3)
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mouse gut metagenome (1)

Repository

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pride (56)
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Tissue

Brain (46)
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Striatal medium spiny neuron differentiation (1)
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Disease

Huntington Disease (10)
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Normal (1)
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Technology Type

Mass Spectrometry (56)
Shotgun proteomics (32)
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Affinity purification coupled with mass spectrometry proteomics (6)
SWATH MS (5)
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Mass spectrometry (1)

Instrument Platform

Illumina HiSeq 4000 (4)
Illumina HiSeq 1500 (3)
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Liquid Chromatography MS - positive (1)
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Liquid Chromatography MS - negative - reverse phase (1)

Publication Date

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2020 (47)
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2017 (25)
2014 (25)
2010 (24)
2015 (23)
2008 (21)
2019 (19)
2011 (17)
2018 (17)
2013 (13)
2007 (12)
2009 (5)
2006 (2)
2005 (1)

UNIPROT ID/AC

P05132 (5)
Q3U214 (3)
Q99PS2 (2)
Q03114 (2)
Q8CA95 (2)
P62137 (2)
Q9ERT9 (2)
P49615 (2)
Q6P1F6 (2)
P63330 (2)
Q60829 (2)
P63328 (2)
P48453 (2)
Q63810 (2)
Q63811 (2)
P48455 (2)
Q9DBC7 (2)
P12849 (2)
P68181 (2)
Q01063 (2)
P62204 (2)
P84309 (2)
P63213 (2)
P62874 (2)
B2RSH2 (2)
Q9UD71 (2)
Q76MZ3 (2)
Q8CGK7 (2)
P61168 (1)
Q60613 (1)

CHEBI ID

CHEBI:17489 (4)
CHEBI:29108 (4)
CHEBI:16027 (4)
CHEBI:18243 (2)
CHEBI:15996 (2)
CHEBI:17552 (2)
CHEBI:15422 (2)
CHEBI:15355 (1)
CHEBI:16335 (1)
CHEBI:45979 (1)
CHEBI:28689 (1)
CHEBI:81281 (1)
CHEBI:16256 (1)
CHEBI:36 (1)
CHEBI:68657 (1)
CHEBI:10070 (1)
CHEBI:38990 (1)
CHEBI:16650 (1)
CHEBI:9884 (1)
CHEBI:88385 (1)
CHEBI:67118 (1)
CHEBI:46053 (1)
CHEBI:30956 (1)
CHEBI:63631 (1)
CHEBI:35014 (1)
CHEBI:9555 (1)
CHEBI:39185 (1)
CHEBI:38747 (1)
CHEBI:9362 (1)
CHEBI:9334 (1)

Metabolite Name

DMePE(44:11+4O) (1)
DMePE(40:8+8O) (1)
DMePE(18:2+3O/22:6) (1)
DMePE(40:8+3O) (1)
DMePE(40:6+4O) (1)
DMePE(22:6+O/17:1) (1)
DMePE(39:7+O) (1)
DMePE(17:0CHO/22:6) (1)
DMePE(39:3e) (1)
DMePE(16:0COOCH3/22:6) (1)
DMePE(38:6) (1)
DMePE(38:3e) (1)
DMePE(38:2e) (1)
DMePE(22:5+2O/15:0) (1)
DMePE(22:3/14:1) (1)
DMePE(36:3e) (1)
DMePE(36:2e) (1)
DMePE(16:0/20:2) (1)
DMePE(36:1+O) (1)
DMePE(35:3e) (1)
DMePE(35:2) (1)
DMePE(20:5+8O/14:1) (1)
DMePE(16:2e/18:1) (1)
DMePE(34:3) (1)
DMePE(34:2e) (1)
DMePE(34:2+OO) (1)
DMePE(30:2e) (1)
DMePE(18:1e) (1)
DMePE(18:0e) (1)
DMePE(16:1e) (1)

First Public Date

2014 (66)
2025 (51)
2026 (49)
2020 (48)
2024 (46)
2022 (46)
2021 (38)
2023 (32)
2017 (27)
2019 (21)
2018 (18)
2016 (14)
2015 (11)
2013 (10)

Modelling Approach

Ordinary differential equation model (11)
Stochastic differential equation model (1)

Study status

Recruiting (1)

Lab affiliation

1The Rappaport Faculty of Medicine and Research Institute, Haifa 3109601, Israel; 2Network Biology Research Laboratories, Technion-Israel Institute of Technology, Haifa 3200003, Israel (2)
Department of Neurological Sciences, University of Nebraska Medical Center, Omaha NE (2)
Neurologische Klinik und Poliklinik des Universitätsklinikums Neurology Josef-Schneider-Straße 11 97080 Würzburg Germany (2)
UCLA (2)
Dept of Neurology University Hospital RWTH Aachen Pauwelsstrasse 30 52074 Aachen Germany (1)
Department for Neurodegenerative Science Van Andel Institute Grand Rapids, MI (1)
Center for Neural Science and Medicine, Board of Governors Regenerative Medicine Institute, Departments of Biomedical Sciences and Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA (1)
Center for Proteome Analysis, Indiana University School of Medicine, Indianapolis, IN (1)
Department of Neurobiology, Northwestern University. (1)
Department of Physiology, Department of Neurobiology, University of California Los Angeles. Los Angeles, CA 90095-1751, USA (1)
Dana Farber Cancer Institute, Boston, MA Harvard Medical School, Boston, MA (1)
Evotec (1)
institute of genetics and developmental biology, Chinese Academy of Sciences (1)
University of Melbourne, Florey Institute (1)
Department of Neurobiology, Northwestern University, Evanston, IL, USA (1)
Department of Physiology and Department of Neurobiology. David Geffen School of Medicine, University of California Los Angeles. Los Angeles, CA 90095-1751, USA (1)
Plateforme Proteome, Univ.Bordeaux (1)
Department of Fundamental Neurosciences, Université de Lausanne, 1005 Lausanne, Switzerland & Department of Biomedicine and Prevention, Università degli studi di Roma "Tor Vergata", 00133 Rome, Italy (1)
School of Life Science and Technology, Southeast University, Nanjing, Jiangsu Province, China (1)
Associate Professor, Neuroscience, The Scripps Research Institute Florida (1)
Evotec (Munchen) GmbH, Am Klopferspitz 19a, 82152 Martinsried, Germany (1)
Evotec (München) GmbH Anna-Sigmund-Str. 5 82061 Neuried Germany (1)
Centre for Neuroscience & Stereology, Neurological Department, Bispebjerg Hospital, Denmark (1)
Department of Neurology, Emory University, Atlanta, GA 30322, US (1)
Department of Pharmacology, Feinberg School of Medicine, Northwestern University (1)
School of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AX, United Kingdom (1)
Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), 50931 Cologne, Germany. (1)
Max Planck Institute for Brain Research (1)
Division of Neurobiology, Department of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore MD (1)
Faculty of Health Sciences, Department of Proteomics, The Novo Nordisk Foundation Centre for Protein Research, University of Copenhagen, DK-2200 Copenhagen, Denmark (1)

IsPrivate

False (12)

Study type

Transcription profiling by array (92)
RNA-seq of coding RNA (20)
ChIP-seq (13)
RNA-seq of coding RNA from single cells (3)
RNA-seq of non coding RNA (3)
ChIP-chip by tiling array (1)
Translation profiling (1)
Cell line - High-throughput sequencing (1)
Methylation profiling by array (1)
Methylation profiling by high throughput sequencing (1)
RNA-seq of total RNA (1)
Observational (1)

Release Date

2022 (477)
2023 (442)
2025 (441)
2021 (433)
2020 (431)
2024 (380)
2018 (358)
2019 (341)
2017 (322)
2016 (300)
2015 (282)
2014 (245)
2012 (142)
2013 (131)
2011 (105)
2010 (88)
2026 (75)
2008 (71)
2009 (67)
2007 (39)
2006 (22)
2005 (20)
2004 (13)
2003 (13)
2001 (6)
2000 (4)
1999 (4)
2002 (3)
1998 (3)
1996 (1)

Location

Belgium (1)

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Striatal microRNA controls cocaine intake through CREB signalling

MicroRNAs (miRNAs) regulate many basic aspects of cell biology including neuronal plasticity, but little is known of their roles in drug addiction. Extended access to cocaine can trigger the emergence of compulsive drug-seeking behaviors, but molecular mechanisms regulating this process remain uncle...

ORGANISM(S): Rattus norvegicus

2010-07-08 | E-GEOD-21901 | biostudies-arrayexpress

Cocaine-regulated expression of striatal microRNAs

We cataloged miRNA expression in the nucleus accumbens and at striatal synapses in control and chronically cocaine-treated mice. We identified cocaine-responsive miRNAs, synaptically-enriched and depleted miRNA families, and confirmed cocaine-induced changes in protein expression for several predict...

ORGANISM(S): Mus musculus

2011-05-13 | E-GEOD-29261 | biostudies-arrayexpress

Chronic stress causes striatal disinhibition mediated by SOM-interneurons

Chronic stress is a major triggering factor for neuropsychiatric disorders including obsessive-compulsive disorder (OCD), a mental health condition characterized by motor stereotypies and striatal overactivation. However, the mechanisms at the cell- and microcircuit-level through which stress trigge...

ORGANISM(S): Mus musculus (Mouse)

2022-12-13 | PXD031193 | Pride

LRRK2 mediates haloperidol-induced changes in striatal indirect pathway circuits

Haloperidol is used to manage psychotic symptoms in several neurological disorders through mechanisms that involve antagonism of dopamine D2Rs that are highly expressed in the striatum. Significant side effects of haloperidol, known as extrapyramidal symptoms, lead to motor deficits similar to those...

ORGANISM(S): Mus musculus (Mouse)

2025-04-25 | PXD053892 | Pride

Striatal Haloperidol Lrrk2

Striatal and hippocampal astrocyte proteomes

We quantitavely compared striatal and hippocampal astrocyte proteomes using stable-isotopic dimethyl labeling.

ORGANISM(S): Mus musculus (Mouse)

2017-07-10 | PXD005852 | Pride

Hippocampus Quantitative Striatum Isotope labeling Astrocyte

Transcription profiling of mouse striatal samples from wildtype, Hdh/Q80 animals

This SuperSeries is composed of the following subset Series:; GSE9375: Striatal gene expression data from 12 months-old Hdh4/Q80 mice and control mice. GSE9857: Striatal gene expression data from 12 weeks-old R6/2 mice and control mice; GSE10202: Striatal gene expression data from 22-month-old CHL2 ...

ORGANISM(S): Mus musculus

2008-05-21 | E-GEOD-10263 | biostudies-arrayexpress

Striatal proteomics of CMS-treated rats

We used a chronic mild stress (CMS) protocol to separate susceptible-depression, susceptible-anxiety and insusceptible rat subgroups. Differential proteomes in the striatal were analyzed based on isobaric tags for relative and absolute quantitation (iTRAQ) labeling combined with mass spectrometry.

ORGANISM(S): Rattus Norvegicus

PXD026107 |

Human striatal organoids derived from pluripotent stem cells recapitulate striatal development and compartments

PRJNA762311 | ENA

Microarray analysis of WT and Drd2-/- striatal tissue from C57BL/6 mice

Drd2 regulates striatal gene networks. WT and KO striatal tissue were dissected from 2-month-old naïve male C57BL/6 genetic background mice and subjected to microarray analysis.

ORGANISM(S): Mus musculus

2012-10-25 | E-GEOD-41638 | biostudies-arrayexpress

FANSseq profiling of human striatal cell types

PRJNA946723 | ENA

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