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ProteomicsProteomic Analysis Based on TMT Regarding the Therapeutic Action of Rhizoma Drynariae on Rats in an Osteoporosis Model
Background: Primary osteoporosis has increasingly become one of the risk factors affecting human health, and the clinical effect and action mechanism of traditional Chinese medicine in the treatment of primary osteoporosis have been widely studied. Previous studies have confirmed that in traditional...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-10-17 | PXD035745 | Pride
Osteoporosis Tmt . Rats Rhizoma drynariae Ovariectomized 
MetabolomicsExogenous L-Alanine promotes phagocytosis multidrug-resistant bacterial pathogens (V. parahaemolyticus-infected spleen metabolomics)

Multidrug-resistant bacteria present a major threat to public health. Therefore, new drugs or approaches are urgently needed to manage and mitigate this threat. Here, we screen the molecular candidates that allow the survival of mice upon Vibrio parahaemolyticus infection by integrated p...

2024-09-26 | MTBLS7996 | MetaboLights
MetabolomicsMetabolomic insights into the browning of the peel of bagging 'Rui Xue' apple fruit

BACKGROUND: Bagging is one of the most important techniques for the production of high-quality fruits. In the act of cultivation, we found a new kind of browning in peel of the apple fruit that occurs before harvest and worsens during the storage period. There are many studies on...

2021-04-09 | MTBLS2384 | MetaboLights
UnknownMultidrug-resistant organisms may be associated with bed allocation and utilization efficiency in healthcare institutions, based on national monitoring data from China (2014-2020).
Not available
S-EPMC10716176 | biostudies-literature
ProteomicsMouse，oocyte ，LC-MS/MS-mRBPome capture of oocytes identifies the RNA-binding protein LSM14B, an essential regulator of meiosis in mouse oocytes
proteins from immunoprecipitation (IP) of LSM14B indentified by mass spectrometry
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD034185 | Pride
Oocyte Mouse Ip Lsm14b 
ProteomicsMus_Oocyte_LC-MS/MS-mRBPome capture of oocytes identifies the RNA-binding protein LSM14B, an essential regulator of meiosis in mouse oocytes
A quantitative mass-spectrometry-based proteome profiles of oocytes in WT and Lsm14b KO mouse
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD034070 | Pride
Wt and lsm14b ko Oocyte Mouse Lc-ms/ms 
ProteomicsProteomic profiling of RNA binding proteins in mouse oocyte
RNA-binding proteins (RBPs) control the fate of RNAs. Tissue regeneration and homeostasis depend on tissue-specific stem cells, but the scope of RBP involvementin these processes remains largely unknown. Here, we identified the RBP repertoire of the mouse oocytes.
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD034071 | Pride
Lc-ms/ms Mouse，oocyte，rbps 
ProteomicsGrass carp serum IgM LC-ESI-MS/MS and MALDI-MS
Glycosylation represents a major post-translational modification of proteins that can influence their structure and function.Telesot immunoglobulin M (IgM) is an especially important product of the immune system because it is the main Abs in seum and plays a critical role against defense infection. ...
ORGANISM(S): Ctenopharyngodon idella 
2018-11-29 | PXD010308 | Pride
Lc-ms/ms) Grass carp Immunoglobulin m Maldi-ms 
ProteomicsDPAGT1-Mediated Protein N-Glycosylation Is Indispensable for Oocyte and Follicle Development in Mice
Posttranslational modification of proteins by N-linked glycosylation is crucial for many life processes. However, the exact contribution of N-glycosylation to mammalian female reproduction remains largely undefined. Here, DPAGT1, the enzyme that catalyzes the first step of protein N-glycosyation, is...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD018531 | Pride
Ovary Lc-ms/ms Mouse 
ProteomicsLiver tumor tissues extracted from a mouse model of hepatocellular carcinoma were subjected to proteomics
The highly metastatic MHCC-97H HCC cell line was orthotopic transplanted into the liver of nude mice to induce orthotopic tumor formation, and lung metastasis was observed. This experimental model not only reproduces the metastasis process of HCC in vivo, but also provides an important biological ma...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD059613 | Pride
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