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MetabolomicsArsenic induces metabolome remodeling in mature human adipocytes
Human lifetime exposure to arsenic through drinking water, food supply or industrial pollution leads to its accumulation in many organs such as liver, kidneys, lungs or pancreas but also adipose tissue. Recently, population-based studies revealed the association between arsenic exposure and the deve...
2025-05-23 | MTBLS8808 | MetaboLights
MetabolomicsCadmium acute exposure induces metabolic and transcriptomic perturbations in human mature adipocytes
Obesity is considered as a major public health concern with strong economic and social burdens. Exposure to pollutants such as heavy metals can contribute to the development of obesity and its associated metabolic disorders, including type 2 diabetes and cardiovascular diseases. Adipose tissue is an...
2023-06-29 | MTBLS4128 | MetaboLights
MetabolomicsBeinaglutide modulates abdominal subcutaneous adipose tissue microenvironment and lipid metabolism in diet-induced obese mice: a multi-omics analysis
Beinaglutide (BN), a recombinant human glucagon-like peptide-1 receptor agonist, exhibits beneficial effects on obesity and metabolic disorders; however, its influence on obesity-related adipose tissue alterations and associated molecular changes remains unclear. In this study, C57BL/6J mice underwe...
2026-09-23 | MTBLS15659 | MetaboLights
MetabolomicsData on changes in lipid profiles during differentiation and maturation of human subcutaneous white adipocytes analyzed using chromatographic and bioinformatics tools
Not available
ORGANISM(S): Homo sapiens 
ST001958 | MetabolomicsWorkbench
ProteomicsData on the change in the protein profiles of human subcutaneous white adipocytes during differentiation and maturation
We analyzed changes in the protein profiles that occur during differentiation and maturation of cultured human subcutaneous white preadipocytes. We divided the three cell lines (Cell Line-1, Cell Line-2, and Cell Line-3) of Caucasian-derived subcutaneous preadipocytes into five stages: i) subcutaneo...
ORGANISM(S): Homo Sapiens (human) 
2022-07-04 | PXD035060 | JPOST Repository
ProteomicsComparative proteomics of human visceral and subcutaneous adipocytes
Adipose tissue (AT) distribution is an important determinant of cardiometabolic health. Increased visceral adiposity has been associated with a higher risk of obesity-related diseases. An important step in deciphering the molecular complexity of subcutaneous AT (SAT) and visceral AT (VAT) is to eluc...
ORGANISM(S): Homo sapiens (Human) 
2021-11-04 | PXD024734 | Pride
Human Lc-msms Obesity Adipocytes Subcutaneous adipose tissue Adipose tissue Visceral adipose tissue 
TranscriptomicsTranscription profiling of human abdominal subcutaneous adipocytes from obese and non-obese Pima Indians
Microarray analysis comparing gene expression profiles of adipocytes from non-diabetic lean vs non-diabetic obese Pima Indian subjects to identify differentially expressed adipocyte genes with obesity. RNA samples of isolated abdominal subcutaneous adipocytes from 20 lean (10 Males / 10 Females, age...
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-2508 | biostudies-arrayexpress
TranscriptomicsMicroarray of isolated adipocytes from subcutaneous adipose tissue of severely obese patients compared to lean controls
The aim of the project was to compare global gene expression in adipocytes from obese patients and lean controls. Subcutaneous adipose tissue was collected from severely obese patients undergoing bariatric surgery (average body-mass index (BMI) of 45.5 kg/m2 (n = 12, thereof 4 men) and healthy lean...
ORGANISM(S): Homo sapiens 
2018-12-12 | E-MTAB-6728 | biostudies-arrayexpress
TranscriptomicsExpression Data from Bone Marrow Progenitor-Derived Adipocytes, White Adipocytes and Brown Adipocytes.
We have identified a population of adipocytes in fat tissue that arise from bone marrow-derived progenitor cells. We used microarrays to compare the global gene expression patterns of the bone marrow progenitor-derived adipocytes as well as conventional white and brown adipocytes to evaluate the rel...
ORGANISM(S): Mus musculus 
2010-01-08 | E-GEOD-19757 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of adipocytes and stromo-vascular fraction from subcutaneous and intraabdominal mouse adipose tissue
Obesity is an epidemic health problem worldwide that impacts the risk and prognosis of many diseases. However, not all obese patients have the same risk of developing these disorders. Individuals with peripheral obesity, i.e., fat distributed subcutaneously, are at little or no risk of the common me...
ORGANISM(S): Mus musculus 
2007-10-31 | E-GEOD-8505 | biostudies-arrayexpress
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