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The transcriptome of rat hippocampal subfields
Hippocampus has drawn an immense attention from researchers and clinicians worldwide due to its clinical importance in various neurodegenerative disorders. Each hippocampal subfield is known to perform distinct functions and are selectively vulnerable to environmental, physiological, and clinical fa...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD029697 | Pride
The hippocampus and entorhinal cortex are the earliest areas affected by AD pathology, which are related to early memory loss in patients. The hippocampus subfields are heterogeneous, with different order and degree affect by AD pathology. Studying the molecular changes may explain the difference, a...
ORGANISM(S): Homo Sapiens 
2021-07-16 | PXD027380 |
RNA sequencing of laser captured hippocampal deep and superficial CA1 subfields in epilepsy
We profiled total mRNA of laser captured microdissected hippocampal deep and superficial CA1 subfields from adult male (45-50 days) Wistar rats (Rattus norvegicus) (180-200g) subjected to kainic acid-induced status epilepticus (chronic epileptic phase) and control animals.
ORGANISM(S): Rattus norvegicus 
2021-05-28 | GSE143555 | GEO
Purpose: In this study, we used LCM and RNA-Seq to characterize differences in the rat hippocampal expression profiles of CA1, CA2, CA3, and DG subfields Methods: Each subfield was bilaterally laser microdissected, collected from the rat's hippocampus (n=4), and submitted to Illuminas for massively ...
ORGANISM(S): Rattus norvegicus 
2021-06-30 | GSE179101 | GEO
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