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ProteomicsProteomics-based identification of potential therapeutic targets of artesunate in a lupus nephritis MRL/lpr mouse model
A total of 6527.0 proteins were identified in the First Affiliated Hospital of Sun Yat sen University, of which 5732.0 proteins contained quantitative information. If we take 1.5 times as the differential expression change threshold and t-test p-value < 0.05 as the significance threshold, we found t...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-24 | PXD046815 | Pride
Lupus nephritis artesunate tmt-based quantitative proteomics 
MetabolomicsMetabolome-based prediction of yield heterosis contributes to the breeding of elite rice
The improvement of breeding efficiencies for heterotic and climate-resilient crops can mitigate the food shortage crisis from overpopulation and climate change. Thus far, diverse molecular markers have been utilized for guiding field phenotypic selections, while the accurate predictions of complex h...
2019-12-10 | MTBLS742 | MetaboLights
ProteomicsDICAR+/- mouse heart Label free LC-MS
The level of ubiquitin protein of the heart of DICAR+/- compared with wild type
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD037732 | Pride
Heart Lc-msms 
ProteomicsIdentification of a biomarker to predict doxorubicin/cisplatin chemotherapy efficacy for osteosarcoma patients by 4D data-independent acquisition (DIA) mass spectrometry with parallel reaction monitoring (PRM) verification
We analyzed the differentially expressed proteins in 37 resected tissue samples from osteosarcoma patients using paraffin- embedded specimens and 4D data-independent acquisition (DIA) quantitative mass spectrometry to investigate biomarkers for predicting the efficacy of doxorubicin/cisplatin chemot...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD051097 | Pride
Osteosarcoma  doxorubicin/cisplatin chemotherapy efficacy  data-independent acquisition (dia) mass spectrometry with parallel reaction monitoring (prm)  ctsg  neutrophil extracellular traps (nets) 
ProteomicsAndrogen Rapidly Activates Phosphorylation Signaling Pathways in Sertoli Cells
This study comprehensively analyzed androgen-activated phosphorylation signaling pathways in testicular Sertoli cells. Primary cultured mouse Sertoli cells were treated with testosterone for varying durations. Using Tandem Mass Tag (TMT)-labeled phosphoproteomics technology combined with Mfuzz clust...
ORGANISM(S): Mus Musculus 
PXD078604 |
UnknownGenome of Crucihimalaya himalaica, a close relative of Arabidopsis, shows ecological adaptation to high altitude.
Not available
S-EPMC6452661 | biostudies-literature
TranscriptomicsIdentification of Rhizome-Specific Genes by Genome-wide Differential Expression Analysis in Oryza longistaminata
The Oryza longistaminata is a perennial wild rice species with AA genome, which characterized by the presence of rhizomatous stem. The rhizomatousness trait in rice was previously identified quantitatively controlled by many genes, but the molecular mechanism related to the rhizome initiation and el...
ORGANISM(S): Oryza longistaminata 
2010-10-31 | E-GEOD-24228 | biostudies-arrayexpress
ProteomicsSIRT5 ameliorates cardiac fibrosis via PCK2 de-succinylation–mediated metabolic reprogramming in cardiac fibroblasts
WT and Sirt5-/- CFBs were stimulated with TGF-β1 (10 ng/mL) for 36 hours. Cells were harvested, snap-frozen, and stored at -80℃. The experiment was independently repeated six times at different time points. Cells from each replicate were pooled to yield more than 3 mg of protein per group. Pooled WT...
ORGANISM(S): Mus Musculus 
2025-11-15 | PXD070811 |
ProteomicsRBM11 drives malignant progression of bladder cancer by regulating GNPDA1-PKM2 axis
This study investigated the biological functions and molecular mechanisms of RNA-binding motif protein 11 (RBM11) in bladder cancer (BCa) progression. Integrated bioinformatics analysis of the TCGA database and validation in clinical tissues revealed that RBM11 is significantly upregulated in BCa an...
ORGANISM(S): Homo Sapiens 
2026-02-26 | PXD074921 |
ProteomicsThe protein binding with diabetes induced circulation associated circular RNA of db/db mouse heart detected by label free LC-MSMS
The protein binding with diabetes induced circulation associated circular RNA (DICAR) pf db/db mouse compared with wild type
ORGANISM(S): Mus Musculus 
PXD037745 |
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