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TranscriptomicsscRNA-seq of Mus musculus subcutaneous Lin- cells derived from the subcutaneous adipose stromal vascular fraction
We used the resolving power of single-cell transcriptional profiling to molecularly characterize the mouse adipose stem and progenitor cell-enriched, subcutaneous adipose stromal vascular fraction. We molecularly assessed CD45- CD31- SVF cells using the 10x Genomics Chromium (10x) platform.
ORGANISM(S): Mus musculus 
2019-05-24 | E-MTAB-6677 | biostudies-arrayexpress
ProteomicsDeep and precise quantification of the mouse synaptosomal proteome reveals substantial remodeling during postnatal maturation
In order to understand the molecular underpinnings of the functional and morphological heterogeneity of synapses and their regulation during development it is essential to identify the set of proteins that form these structures. Here, we prepared cortical synaptosomal fractions from juvenile and adu...
ORGANISM(S): Mus musculus (Mouse) 
2014-08-28 | PXD000552 | Pride
Synapse proteome ageing 
ProteomicsPlasma and crude membrane fraction from mouse liver and kidney
The purpose of the present study was to validate the enrichment of transporter proteins in plasma membrane fraction prepared from mouse liver and kidney with Membrane Protein Extraction Kit by means of beads homogenize for efficient subcellular fractionation. The crude and plasma membrane fractions ...
ORGANISM(S): Mus Musculus (mouse) 
2020-09-26 | PXD018161 | JPOST Repository
ProteomicsSynaptosomal proteome from schizophrenia patients
Proteomic characterization of the synaptosome fraction of the orbitofrontal cortex using label-free and iTRAQ labeling strategies.
ORGANISM(S): Homo sapiens (Human) 
2017-09-29 | PXD006798 | Pride
Schizophrenia Synaptosome Quantitative proteomics 
ProteomicsProteomics quantification of striatal fraction from DAT-KO and WT rats
The study aimed to find out quantitative changes at the protein level in the total membrane fraction enriched in synaptosomes and mitochondria upon the absence of the dopamine transporter in rat brain. Therefore, the brain of male rats (Wister Han) DAT-wildtype and DAT-knockout animals, were dissect...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-05-19 | PXD028157 | Pride
Lc-msms Dat-ko Knockout Striatum Rat Brain Dat Proteomics Dopamine transporter 
ProteomicsSynaptosomal proteome from schizophrenia patients
Proteomic characterization of the synaptosome fraction of the orbitofrontal cortex using label-free and iTRAQ labeling strategies.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-10-30 | MSV000086389 | MassIVE
TranscriptomicsTranscriptomic effect of parental exposure to a crude oil water-soluble fraction in Atlantic cod (Gadus morhua) early life stages
This study investigates how parental exposure to the water-soluble fraction (WSF) of crude oil influences transcriptomic profiles in Atlantic cod (Gadus morhua) offspring. Fish were exposed to WSF for 20 days prior to spawning, and four offspring groups were generated by fertilization: control (unex...
ORGANISM(S): Gadus morhua 
2026-02-16 | E-MTAB-16384 | biostudies-arrayexpress
ProteomicsProteomic characterization of synaptosomes and sarkosyl-insoluble protein inclusions from Alzheimer's disease patients
Alzheimer’s disease is characterized by neuropathological accumulation of amyloid plaques and neurofibrillary tangles composed of amyloid-beta peptides and hyperphosphorylated tau protein, respectively. These neuropathological changes alter the function of neurons, including synaptic contacts betwee...
ORGANISM(S): Homo sapiens (Human) 
2026-07-09 | PXD070075 | Pride
Human Synaptosomes Brain Alzheimer's disease Sarkosyl-insoluble fraction 
ProteomicsRepeated hypoglycemia in diabetic mice induce hypothalamic mitochondrial and synaptic activity deregulations characteristic of neurodegenerative diseases
Repeated exposures to insulin-induced hypoglycemia in diabetic patients progressively impair the counter-regulatory response (CRR) that restores normoglycemia. This defect is characterized by reduced secretion of glucagon and other counter-regulatory hormones. Evidence indicates that glucose respons...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-13 | PXD040183 | Pride
Hypothalamus Synaptosomal fractions Hypoglycemia Whole lysate Mouse Diabetes 
ProteomicsProteomics of the Bee brain and in olfactory memory
Previous work has shown that a series of honey bee brain proteins were probably linked to the proboscis extension reflex (PER) , a model studying insect behaviour. Herein, it was the aim of the study to generate a “synaptic proteome” and to investigate which proteins were paralleling olfactory cond...
ORGANISM(S): Apis mellifera (Honeybee) 
2019-05-27 | PXD011217 | Pride
Proboscis Bee Brain Olfactory memory 
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