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GenomicsTargeted DamID of selected chromatin proteins in quiescent and proliferating neural stem cells
Targeted DamID of embryonic proliferating (epNSCs), quiescent (qNSCs) and larval proliferating neural stem cells (lpNSCs) was performed using worniu-GAL4, tubGAL80ts (for qNSCs and lpNSCs condition) or worniu-GAL4 (for epNSCs condition) as a driver to express nine different Dam-fusions and Dam on it...
ORGANISM(S): Drosophila melanogaster 
2025-11-11 | E-MTAB-15696 | biostudies-arrayexpress
MetabolomicsIntegration of time-series meta-omics data reveals how microbial ecosystems respond to disturbance
The development of reliable, mixed-culture biotechnological processes hinges on understanding how microbial ecosystems respond to disturbances. Here we reveal extensive phenotypic plasticity and niche complementarity in oleaginous microbial populations from a biological wastewater treatment plant. W...
2021-04-06 | MTBLS2021 | MetaboLights
ProteomicsA patient-based Drosophila model for mitochondrial S-Adenosylhomocysteine transport deficiency
The SLC25A26 gene encodes a mitochondrial inner membrane carrier that transports S-adenosylmethionine (SAM) into the mitochondrial matrix in exchange for S-adenosylhomocysteine (SAH). SAM is the predominant methyl-group donor for most cellular methylation processes, of which SAH is produced as a by-...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2022-01-19 | PXD026900 | Pride
Sam Samc Methylation Sah Mitochondria Drosophila Slc25a26 
TranscriptomicsGene expression and genotype in normal heart
Genome-wide association studies have identified a small region at chromosome 9p21.3 strongly associated with coronary heart disease risk. The region contains no protein-coding genes and the mechanism underlying its association with heart disease is unknown. We investigated associations between rs133...
ORGANISM(S): Homo sapiens 
2012-07-03 | E-GEOD-22253 | biostudies-arrayexpress
ProteomicsN-terminal processing of beta and gamma actin in human platelets
Actin is one of the most essential and abundant intracellular proteins, playing an essential physiological role as the major constituent of the actin cytoskeleton. Two cytoplasmic actins, beta- and gamma-actin, are encoded by different genes, but their amino acid sequences differ only by four conser...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD032086 | Pride
Actin Human Platelet 
ProteomicsN-terminal processing of beta and gamma actin in HAP1 cells
Actin is one of the most essential and abundant intracellular proteins, playing an essential physiological role as the major constituent of the actin cytoskeleton. Two cytoplasmic actins, beta- and gamma-actin, are encoded by different genes, but their amino acid sequences differ only by four conser...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD031481 | Pride
Actin Human Hap1 
ProteomicsN-terminal processing of beta and gamma actin in MEF cells
Actin is one of the most essential and abundant intracellular proteins, playing an essential physiological role as the major constituent of the actin cytoskeleton. Two cytoplasmic actins, beta- and gamma-actin, are encoded by different genes, but their amino acid sequences differ only by four conser...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD032139 | Pride
Mouse Mef Actin 
ProteomicsMitochondrial interactome quantitation reveals structural changes in metabolic machinery in the failing murine heart
Advancements in cross-linking mass spectrometry (XL-MS) for structural analysis of proteins bridge the gap between purified systems and native tissue environments. Here, isobaric quantitative protein interaction reporter technology (iqPIR) was utilized to further extend XL-MS to the first system-wid...
ORGANISM(S): Mus musculus (Mouse) 
2023-02-27 | PXD035712 | Pride
Quantitative cross-linking  heart failure  cardiac hypertrophy  mitochondria  protein interactions  interactome  mass spectrometry  systems structural biology 
TranscriptomicsEpigenetic targeting of activation-induced cytidine deaminase
Precisely how AID is recruited to these off-target sites is not entirely understood. To gain further insight into how AID selects its targets we compared AID-mediated translocations in two different cell types, B cells and mouse embryonic fibroblasts (MEFs). AID targets a distinct set of hotspots in...
ORGANISM(S): Mus musculus 
2015-01-30 | E-GEOD-61523 | biostudies-arrayexpress
UnknownMolecular effects of indoor tanning.
Not available
S-EPMC12700204 | biostudies-literature
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