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MetabolomicsOlive Oil Authenticity Studies by Target and Non-target LC-QTOF-MS combined with Advanced Chemometric Techniques
Food analysis is continuously requesting the development of more robust, efficient and cost-effective food authentication analytical methodologies to guarantee the safety, quality and traceability of food commodities with respect to legislation and consumer demands. Hence, a novel RP-UHPLC-ESI-QTOF-...
2017-05-04 | MTBLS433 | MetaboLights
ProteomicsIdentification of proximal SUMO-dependent interactors using SUMO-ID
To study the function of SUMOylation and SUMO-SIM interactions for particular substrates poses several challenges. SUMOylation occurs transiently and often in a small percentage of the total copy numbers of a given substrate. Modified proteins can be readily deSUMOylated and SUMO can be recycled and...
ORGANISM(S): Homo sapiens (Human) 
2021-09-21 | PXD021923 | Pride
Human Turbo-id Proximity labeling Sall1 Sumo-id Sumo 
ProteomicsCompetitive target ID for inhibitor NK192
Competitive target ID for inhibitor NK192. To this end the inhibitor was decorated with biotin and used in a pull-down experiment to pull out the desired on-target (USP7) and possible off-targets. The samples were analysed by LC-MS.
ORGANISM(S): Homo sapiens (Human) 
2026-04-21 | PXD063889 | Pride
Usp7 Lc-ms Pull-down 
GenomicsCUT&ID of 8 targets in HCT116
CUT&ID of 8 targets in HCT116
PRJEB105294 | ENA
ProteomicsSMAP3-ID for identification of protein-protein interactions in native cells
Proteins regulate biological functions through formation of distinct protein complexes. Identification and characterization of these protein-protein interactions are critical to decipher their mechanism of action. Different antibody- or crosslinking-based methods have been developed to identify the ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-25 | PXD054249 | Pride
Lamin Smap3-id Protein-protein interaction Lbl1-pcf Native 
MetabolomicsMultiomic profiling of iron-deficient infant monkeys reveals alterations in neurologically important biochemicals in serum and cerebrospinal fluid before the onset of anemia

The effects of iron deficiency (ID) during infancy extend beyond the hematologic compartment and include short- and long-term adverse effects on many tissues including the brain. However, sensitive biomarkers of iron-dependent brain health are lacking in humans. To determine whether serum and cer...

2022-07-12 | MTBLS3388 | MetaboLights
TranscriptomicsTo compare the expression profile of CD8 T cells from mice vaccinated with Ad85A via the intranasal (IN) or intradermal (ID) routes isolated from lungs or spleen.
In Balb/c mice, the presence of effector CD8 T cells in lungs after intra-nasal (IN) immunization with replication deficient recombinant Adenovirus expressing the 85A antigen from Mycobacterium tuberculosis (MTb) (Ad85A) correlates with protection against aerosol MTb infection. In order to identify ...
ORGANISM(S): Mus musculus 
2010-08-24 | E-GEOD-23713 | biostudies-arrayexpress
TranscriptomicsCell-context dependent Notch target genes
Notch signaling regulates a variety of developmental cell fates decisions in a cell-context dependent manner. Although Notch signaling directly regulates transcription via the RBP-J/CSL DNA binding protein, little is known about the genes in the respective tissues that are directly activated by Notc...
ORGANISM(S): Mus musculus 
2010-07-13 | E-GEOD-15268 | biostudies-arrayexpress
MetabolomicsMetabolomics reveals molecular signatures for psoriasis biomarkers and drug targets discovery
Psoriasis is a chronic skin disease that affects multiple systems and can be influenced by immunological, environmental, and genetic factors. The discovery of plasma biomarkers of psoriasis and the regulation of metabolic pathways helps us understand psoriasis and may assist clinicians in the diagno...
2024-09-26 | MTBLS5185 | MetaboLights
UnknownId-1 is a key transcriptional regulator of glioblastoma aggressiveness and a novel therapeutic target.
Not available
S-EPMC3594064 | biostudies-literature
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