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UnknownRemodeling of intracellular architecture during SARS-CoV-2 infection of human endothelium.
Not available
S-EPMC11608320 | biostudies-literature
UnknownReversible rearrangement of the cellular cytoskeleton: A key to the broad-spectrum antiviral activity of novel amphiphilic polymers.
Not available
S-EPMC10433002 | biostudies-literature
UnknownEndothelial glycocalyx shields the interaction of SARS-CoV-2 spike protein with ACE2 receptors.
Not available
S-EPMC8190434 | biostudies-literature
UnknownCirculating ectosomes: Determination of angiogenic microRNAs in type 2 diabetes.
Not available
S-EPMC6071541 | biostudies-literature
UnknownAFM-based detection of glycocalyx degradation and endothelial stiffening in the db/db mouse model of diabetes.
Not available
S-EPMC5698475 | biostudies-literature
ProteomicsKeap-1-mediated S-nitrosylation of NOX4 hampers oxidative damage in endothelium
ABSTRACT Rationale Premature senescence is conducive to aging and cardiovascular diseases. Nrf2 transcription factor, the master orchestrator of adoptive response to cellular stress, has been implicated in regulation of premature senescence in fibroblasts, neural and mesenchymal stem cells by trans...
ORGANISM(S): Homo sapiens (Human) 
2020-08-12 | PXD013640 | Pride
Endothelial cells S-nitrosylation Nrf2 Nox4 Oxidative stress 
UnknownKeap1 governs ageing-induced protein aggregation in endothelial cells.
Not available
S-EPMC7327977 | biostudies-literature
UnknownDegradation of Glycocalyx and Multiple Manifestations of Endothelial Dysfunction Coincide in the Early Phase of Endothelial Dysfunction Before Atherosclerotic Plaque Development in Apolipoprotein E/Low-Density Lipoprotein Receptor-Deficient Mice.
Not available
S-EPMC6475045 | biostudies-literature
TranscriptomicsRNA-seq of hiPSC-ECs from HNF1A-MODY patient and corrected isogenic control lines
The experiment aims to find differences in gene expression in endothelial cells due to a heterozygous mutation in HNF1A, which cause maturity-onset diabetes of the young (MODY). For that purpose human induced pluripotent stem cell (hiPSCs) line from an HNF1A-MODY patient was repaired using CRISPR/Ca...
ORGANISM(S): Homo sapiens 
2026-02-22 | E-MTAB-16548 | biostudies-arrayexpress
ProteomicsKeap1 governs ageing-induced protein aggregation in endothelial cells
The breach of proteostasis, leading to the accumulation of protein aggregates, is a hallmark of ageing and age-associated disorders, up to now well-established in neurodegeneration. Few studies have addressed the issue of dysfunctional cell response to protein deposition also for the cardiovascular ...
ORGANISM(S): Homo sapiens (Human) 
2020-08-12 | PXD018969 | Pride
Aggregates Keap1 Human 
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