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ProteomicsProtein profiling of 6-OHDA induced PD Model treated by TBN
Parkinson's disease (PD) listed as the second most common neurodegenerative disease. 2-[[(1,1-Dimethylethyl)oxidoimino]-methyl]-3,5,6-trimethylpyrazine (TBN), a novel nitrone derivative of tetramethylpyrazine, has shown benefits for the treatment both in vitro and in vivo, TBN protects and rescues d...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-03-02 | PXD004812 | Pride
Tbn Rat model 6-ohda Parkinson's disease 
UnknownNephroprotective Effects of Tetramethylpyrazine Nitrone TBN in Diabetic Kidney Disease.
Not available
S-EPMC8264657 | biostudies-literature
ProteomicsEvaluation of therapeutic effects of tetramethylpyrazine nitrone in Alzheimer’s disease mouse model and proteomics analysis
The pathophysiology of Alzheimer’s disease (AD) is multifactorial with characteristic extracellular accumulation of amyloid-beta (Aβ) and intraneuronal aggregation of hyperphosphorylated tau in the brain. Development of disease-modifying treatment for AD has been challenging. Recent studies suggest ...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD039514 | Pride
Amyloid beta Alzheimer’s disease Pink1. Tetramethylpyrazine nitrone Proteomic analysis 
UnknownChitosan Nanoparticles Loaded Poloxamer 407 Gel for Transungual Delivery of Terbinafine HCl.
Not available
S-EPMC9698022 | biostudies-literature
UnknownSelf-reported treatment burden: A comparison between vitamin K and non-vitamin K oral anticoagulants.
Not available
S-EPMC12269622 | biostudies-literature
UnknownPrimary tracheobronchial necrosis after esophagectomy: A nationwide multicenter retrospective study in Japan.
Not available
S-EPMC10043765 | biostudies-literature
UnknownAssessment of patient-reported treatment burden in patients with coronary artery disease.
Not available
S-EPMC11264058 | biostudies-literature
UnknownTetramethylpyrazine nitrone exerts neuroprotection via activation of PGC-1α/Nrf2 pathway in Parkinson's disease models.
Not available
S-EPMC11464467 | biostudies-literature
UnknownEvaluation of therapeutic effects of tetramethylpyrazine nitrone in Alzheimer's disease mouse model and proteomics analysis.
Not available
S-EPMC10025301 | biostudies-literature
UnknownTetramethylpyrazine nitrone, a multifunctional neuroprotective agent for ischemic stroke therapy.
Not available
S-EPMC5107909 | biostudies-literature
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